N*1*-(6-Morpholin-4-yl-3-nitro-4-(trifluoromethyl)-pyridin-2-yl)ethane-1,2-diamine CAS 1053658-12-0
| CAS No. | 1053658-12-0 |
| Molecular Formula | C12H16F3N5O3 |
| Molecular Weight | 335.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N*1*-(6-Morpholin-4-yl-3-nitro-4-(trifluoromethyl)-pyridin-2-yl)ethane-1,2-diamine (CAS 1053658-12-0), molecular formula C12H16F3N5O3 and molecular weight 335.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N*1*-(6-Morpholin-4-yl-3-nitro-4-(trifluoromethyl)-pyridin-2-yl)ethane-1,2-diamine (C12H16F3N5O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N*1*-(6-Morpholin-4-yl-3-nitro-4-(trifluoromethyl)-pyridin-2-yl)ethane-1,2-diamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H16F3N5O3 |
| Molecular Weight | 335.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related N Standards
- 2-[2-(Morpholin-4-yl)-2-oxoethyl]-9,10-dihydroanthracene-9,10-dione (CAS 338968-34-6)
- N-[2-(Morpholin-4-yl)ethyl]-5-nitro-1-benzothiophene-2-carboxamide (CAS 478076-68-5)
- 8-(MOrpholin-4-ylsulfonyl)-5h-[1,2,4]triazino[5,6-b]indol-3-amine (CAS 910443-22-0)
- 3-(2-Morpholin-4-yl-5-trifluoromethyl-pyridin-3-yl)-benzaldehyde (CAS 1311278-45-1)
- 4-(2-Morpholin-4-yl-5-trifluoromethyl-pyridin-3-yl)-benzaldehyde (CAS 1311279-52-3)
- (6-Morpholin-4-yl-4-(trifluoromethyl)-pyridin-2-ylsulfanyl)acethydrazide (CAS 1053657-62-7)
- Methyl (6-morpholin-4-yl-4-(trifluoromethyl)-pyridin-2-ylsulfanyl)acetate (CAS 1053659-80-5)
- N-[6-(Morpholin-4-yl)pyridin-3-yl]-1-phenylmethanesulfonamide (CAS 439095-82-6)
Recommended Standards
- 4-((1,3-Dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl)oxy)benzaldehyde (CAS 1031928-98-9)
- 2'-Bromospiro[[1,3]dithiolane-2,9'-fluorene] (CAS 113425-37-9)
- ethyl 3-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate (CAS 1018125-43-3)
- 7-[(tert-Butoxy)carbonyl]-3-(trifluoromethyl)-5H,6H,7H,8H-imidazo[1,5-a]pyrazine-1-carboxylic acid (CAS 1174039-46-3)
- (2e)-3-(2,5-Dimethyl-1-propyl-1h-pyrrol-3-yl)prop-2-enoic acid (CAS 851175-84-3)
- 161125-38-8 5155AD C22H23NO6 Fmoc-DL-2-aminoheptanedioic acid (CAS 161125-38-8)
- Methyl 3-(2,4-dichlorophenyl)-3-methyloxirane-2-carboxylate (CAS 1499520-97-6)
- Methyl 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-3-carboxylate hydrochloride (CAS 2137768-58-0)
- Afoxolaner Impurity 34 (CAS CATO-C4X-313734)
- 3-Fluoro-3'-(pyrrolidin-1-ylsulfonyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 1261941-05-2)
- Methyl (8Z,11Z,14Z,17Z)-8,11,14,17-eicosatetraenoate (CAS 132712-70-0)
- 4-(4-Benzylphenoxy)-3-(trifluoromethyl)aniline (CAS 946740-90-5)
- 4,5-Dichloro-1,2,3-dithiazol-1-ium chloride (CAS 75318-43-3)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
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