4-Bromo-1-[chloro(difluoro)-methoxy]-2-fluoro-benzene CAS 105529-59-7

Purity 97%+In StockPharmaceutical Standards
CAS No.105529-59-7
Molecular FormulaC7H3BrClF3O
Molecular Weight275.45 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Bromo-1-[chloro(difluoro)-methoxy]-2-fluoro-benzene CAS 105529-59-7 chemical structure

Description

The occurrence of 4-Bromo-1-[chloro(difluoro)-methoxy]-2-fluoro-benzene is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Bromo-1-[chloro(difluoro)-methoxy]-2-fluoro-benzene (CAS 105529-59-7) is a high-purity analytical reference standard with the molecular formula C7H3BrClF3O and a molecular weight of 275.45 g/mol.

Owing to a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system, 4-Bromo-1-[chloro(difluoro)-methoxy]-2-fluoro-benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 275.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H3BrClF3O
Molecular Weight275.45 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl/Br-containing

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