(4-(2,2,2-Trifluoroacetyl)phenyl)boronic acid CAS 1055316-64-7
| CAS No. | 1055316-64-7 |
| Molecular Formula | C8H6BF3O3 |
| Molecular Weight | 217.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(4-(2,2,2-Trifluoroacetyl)phenyl)boronic acid (CAS 1055316-64-7), molecular formula C8H6BF3O3 and molecular weight 217.94 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4-(2,2,2-Trifluoroacetyl)phenyl)boronic acid (C8H6BF3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H6BF3O3 |
| Molecular Weight | 217.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Trifluoroacetyl Standards
- 2-(2,2,2-Trifluoroacetyl)benzoic acid (CAS 203124-56-5)
- 3-(2,2,2-Trifluoroacetyl)benzoic acid (CAS 213598-05-1)
- 4-(2,2,2-Trifluoroacetyl)benzoic acid (CAS 58808-59-6)
- (6-(2,2,2-Trifluoroacetyl)pyridin-3-yl)boronic acid (CAS 1310384-03-2)
- (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS 1310404-58-0)
- 7-(2,2,2-Trifluoroacetyl)-1,2,3,6-tetrahydro-5H-pyrrolo[1,2-a]imidazol-5-one (CAS 1263215-92-4)
- 4-Methyl-1-(2,2,2-trifluoroacetyl)piperidine-4-carbonitrile (CAS 1443980-84-4)
- 2-(2,2,2-Trifluoroacetyl)hexahydrocyclopenta[c]pyrrol-5(1H)-one (CAS 1263280-07-4)
Recommended Standards
- 1,2,3,5-Tetrachlorobenzene-d2 (CAS 2199-74-8)
- (4-Formyl-3-(trifluoromethyl)phenyl)boronic acid (CAS 1072944-24-1)
- 1,2,3,4-Tetrachlorobenzene-d2 (CAS 2199-73-7)
- (2-Formyl-5-(trifluoromethyl)phenyl)boronic acid (CAS 1204580-94-8)
- 1-(4-(4-Acetyl-2-chlorophenyl)piperazin-1-yl)ethan-1-one (CAS 1283466-18-1)
- N-Phenyl-4-(quinolin-3-ylmethyl)piperazine-1-carboxamide (CAS 898235-65-9)
- 1-[3-(4-Bromobenzenesulfonyl)propoxy]-3-(trifluoromethyl)benzene (CAS 338792-71-5)
- Daclatasvir Impurity 8 (CAS CATO-C4X-18488)
- Vinpocetine Impurity 23 (CAS CATO-C4X-184323)
- 1,6-dimethyl-1,2-dihydro-1,5-naphthyridin-2-one (CAS 859986-81-5)
- 4-Chloro-1,3-dihydroxypyridin-2(1H)-one (CAS 19352-46-6)
- 7-Methyl-5-oxa-2-azaspiro[3.4]Octane (CAS 2306260-93-3)
- 3-(isocyanatomethyl)-1-methyl-1,2,4-triazole (CAS 2795115-66-9)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
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