7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine CAS 105679-22-9

Purity 97%+In StockPharmaceutical Standards
CAS No.105679-22-9
Molecular FormulaC8H8BrNO
Molecular Weight214.06 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine CAS 105679-22-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine.

CATO supplies 7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 105679-22-9), a certified reference material (molecular formula C8H8BrNO, MW 214.06 g/mol) for analytical method development and quality control.

Structurally, 7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine (C8H8BrNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 214.06 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H8BrNO
Molecular Weight214.06 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentBr-containing
Nitrogen Atoms1

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