Thieno[2,3-b]pyridin-2-amine CAS 1057326-75-6
| CAS No. | 1057326-75-6 |
| Molecular Formula | C7H6N2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 186.66 g/mol gives Thieno[2,3-b]pyridin-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Thieno[2,3-b]pyridin-2-amine (CAS 1057326-75-6) is a high-purity analytical reference standard with the molecular formula C7H6N2SHCl and a molecular weight of 186.66 g/mol.
Structurally, Thieno[2,3-b]pyridin-2-amine (C7H6N2SHCl) contains a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 186.66 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Thieno[2,3-b]pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6N2S HCl |
| Molecular Weight | 186.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Thieno Standards
- 4H-thieno[3,2-b]pyrrole-2-carboxylic acid (CAS 1007386-84-6)
- Thieno[2,3-c]pyridin-2-ylboronic acid (CAS 1018954-04-5)
- 5H-thieno[3,2-b]pyran-2-carboxylic acid (CAS 1020936-98-4)
- Thieno[3,2-d]pyrimidin-2-amine (CAS 1027729-09-4)
- Thieno[2,3-d]pyrimidin-4-ylproline (CAS 1028366-39-3)
- methyl thieno[3,2-d]pyrimidine-4-carboxylate (CAS 1029144-47-5)
- thieno[3,2-d]pyrimidine-4-carboxylic acid (CAS 1029144-49-7)
- 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-dione (CAS 103979-54-0)
Recommended Standards
- Dihydrodigoxin (CAS 5297-10-9)
- Ethyl 4-formyl-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate (CAS 1159691-45-8)
- n1-((1h-Imidazol-2-yl)methyl)-n2,n2-dimethylethane-1,2-diamine (CAS 921161-00-4)
- (2S,4R)-4-benzylpyrrolidine-2-carboxylic acid hydrochloride (CAS 1279049-67-0)
- 3-amino-5-methylbenzamide (CAS 1169516-89-5)
- 2,6-dibromo-4-fluorobenzene-1-sulfonamide (CAS 1094671-84-7)
- 2-(3-Methylureido)benzoic acid (CAS 4141-12-2)
- Hemicholinium (CAS 16478-59-4)
- 3-Bromo-4-chloro-pyridine-2-carbaldehyde (CAS 1289031-51-1)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788692)
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