3,5-Dimethylbiphenyl-4-ylboronic acid CAS 1057654-43-9
| CAS No. | 1057654-43-9 |
| Molecular Formula | C14H15BO2 |
| Molecular Weight | 226.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,5-Dimethylbiphenyl-4-ylboronic acid (CAS 1057654-43-9) is a high-purity analytical reference standard with the molecular formula C14H15BO2 and a molecular weight of 226.08 g/mol.
The molecular framework of 3,5-Dimethylbiphenyl-4-ylboronic acid (C14H15BO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H15BO2 |
| Molecular Weight | 226.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
Related Dimethylbiphenyl Standards
- 2',4'-Dimethylbiphenyl-3-carboxylic acid (CAS 1170419-33-6)
- 2',5'-Dimethylbiphenyl-3-carboxylic acid (CAS 1181626-10-7)
- 2',3'-Dimethylbiphenyl-3-carboxylic acid (CAS 1215206-78-2)
- 2',6'-Dimethylbiphenyl-3-carboxylic acid (CAS 955929-56-3)
- MEthyl 4',4-dimethylbiphenyl-2-carboxylate (CAS 216442-81-8)
- 2’,6’-Dimethylbiphenyl-3-carbaldehyde (CAS 691905-26-7)
- 2,3’-dimethylbiphenyl (CAS 611-43-8)
- 2,4'-Dimethylbiphenyl (CAS 611-61-0)
Recommended Standards
- 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carbaldehyde (CAS 1055881-23-6)
- (2-Chloropyridin-4-yl)methanesulfonyl chloride (CAS 1062069-19-5)
- 2,6-Dichlorobenzenesulfonamide (CAS 10290-98-9)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)tetrahydro-2H-pyran-2-one (CAS 1159919-02-4)
- N-(2-aminoethyl)-2-bromo-5-methylbenzene-1-sulfonamide hydrochloride (CAS 1604485-82-6)
- 5-Methyl-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 61404-87-3)
- 5-Bromo-2-(pyrrolidin-2-yl)thiazole (CAS 1505570-79-5)
- 1-(2-Chlorophenyl)-3-(trifluoromethyl)-1h-pyrazol-5-amine (CAS 437711-26-7)
- (16α)-9-Fluoro-16,17,21-trihydroxy-pregna-1,4-diene-3,11,20-trione 16, 21-Diacetate (CAS 1868-22-0)
- 3-Aminobenzene-1,2-diol hydrochloride (CAS 51220-97-4)
- 3-imidazo[1,2-a]pyrimidin-3-ylprop-2-yn-1-amine;2,2,2-trifluoroacetic acid (CAS 2698371-51-4)
- 5-acetyl-3-methylthieno[2,3-b]pyridine-2-carboxylic acid (CAS 1050885-00-1)
- 1-Hydroxy-2(1H)-pyridinone (CAS 822-89-9)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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