4,6-Dichloro-5-fluoro-2-methylpyrimidine CAS 105806-13-1
| CAS No. | 105806-13-1 |
| Molecular Formula | C5H3Cl2FN2 |
| Molecular Weight | 181.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,6-Dichloro-5-fluoro-2-methylpyrimidine is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4,6-Dichloro-5-fluoro-2-methylpyrimidine (CAS 105806-13-1), molecular formula C5H3Cl2FN2 and molecular weight 181.00 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, fluorine/chlorine substitution, 4,6-Dichloro-5-fluoro-2-methylpyrimidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4,6-Dichloro-5-fluoro-2-methylpyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl2FN2 |
| Molecular Weight | 181.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 3,5-Dichloro-6-fluoropyridin-2-amine (CAS 1261269-88-8)
- 3,5-Dichloro-2-fluoropyridin-4-amine (CAS 1364917-12-3)
- 4,6-Dichloro-2-(fluoromethyl)pyrimidine (CAS 16097-55-5)
- 3,5-Dichloro-4-fluoropyridin-2-amine (CAS 1935083-06-9)
- 2,4-Dichloro-5-fluoro-6-methylpyrimidine (CAS 954220-98-5)
- 2,6-Dichloro-3-fluoropyridin-4-amine (CAS 2051921-49-2)
- 2,5-Dichloro-3-fluorophenol (CAS 1394927-62-8)
- 2,6-Dichloro-3-fluorophenol (CAS 1803854-58-1)
Recommended Standards
- 3,6-Dichloro-2-fluorophenol (CAS 916420-67-2)
- (6-(2-Hydroxypropan-2-yl)pyridin-3-yl)boronic acid (CAS 1088496-42-7)
- 3,5-Dichloro-4-fluorophenol (CAS 2995-04-2)
- (2-Isopropoxypyridin-3-yl)boronic acid (CAS 1150114-42-3)
- L-Homotyrosine Hydrobromide (CAS 141899-12-9)
- 2-Hydroxy-N-(2-(methylthio)phenyl)benzamide (CAS 447413-03-8)
- 5-(Thiazolidin-3-yl)nicotinaldehyde (CAS 1713160-16-7)
- 2-Ethyl-5-(4-methoxyphenyl)furan (CAS 62596-42-3)
- 4-{2-[2-Bromo-4-(sec-butyl)phenoxy]-ethyl}piperidine hydrochloride (CAS 1219956-86-1)
- 2-(2-Methylpiperidin-1-yl)nicotinonitrile (CAS 945347-49-9)
- 4-Iodobutyl Pivalate (CAS 82131-05-3)
- 9-amino-5-azaspiro[3.5]nonan-6-one (CAS 1803603-81-7)
- Calcium acetate (CAS 62-54-4)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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