2-(4-Chlorophenoxy)-N-(thiophen-3-ylmethyl)acetamide CAS 1058195-46-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1058195-46-2
Molecular FormulaC13H12ClNO2S
Molecular Weight281.76 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-Chlorophenoxy)-N-(thiophen-3-ylmethyl)acetamide CAS 1058195-46-2 chemical structure

Description

The molecular framework of 2-(4-Chlorophenoxy)-N-(thiophen-3-ylmethyl)acetamide (C13H12ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

2-(4-Chlorophenoxy)-N-(thiophen-3-ylmethyl)acetamide (CAS 1058195-46-2) is a high-purity analytical reference standard with the molecular formula C13H12ClNO2S and a molecular weight of 281.76 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H12ClNO2S
Molecular Weight281.76 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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