Atrasentan Impurity 135 CAS 1058349-10-2
| CAS No. | 1058349-10-2 |
| Molecular Formula | C31H42N2O6 |
| Molecular Weight | 538.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Atrasentan Impurity 135 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Atrasentan Impurity 135 (CAS 1058349-10-2, C31H42N2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Atrasentan Impurity 135 (C31H42N2O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Atrasentan Impurity 135 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C31H42N2O6 |
| Molecular Weight | 538.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 118 (CAS 1059759-94-2)
- Atrasentan Impurity 119 (CAS 209214-33-5)
- Atrasentan Impurity 121 (CAS 195708-08-8)
- Atrasentan Impurity 138 (CAS 1058349-16-8)
- Atrasentan Impurity 157 (CAS 1073727-25-9)
- Atrasentan Impurity 163 (CAS 1059025-59-0)
- Atrasentan Impurity 171 (CAS 1059051-90-9)
- Atrasentan Impurity 43 (CAS 223139-35-3)
Recommended Standards
- 6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (CAS 5987-76-8)
- 3,3''-(((1R,2R)-Cyclohexane-1,2-diylbis(azanediyl))bis(methylene))bis(2'-methoxy-[1,1'-biphenyl]-2-ol) (CAS 928769-12-4)
- 1,4-Bis(bis(3,5-dimethylphenyl)phosphino)butane (CAS 220185-37-5)
- Atrasentan Impurity 72 (CAS 1058404-69-5)
- Lufenuron EP Impurity H (CAS CATO-C4X-28877)
- Gadobutrol Impurity 4 （And Enantiomer） (CAS CATO-C4X-21204)
- Vigabatrin Impurity 2 (CAS CATO-C4X-11962)
- (S)-4-(N,N-Dimethylaminosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole (CAS 143112-50-9)
- (R)-7-methyl-1-(oxetan-3-yl)-1,4-diazepane (CAS 2165746-92-7)
- Methyl 2-(4-fluorophenyl)imidazo[1,2-a]pyridine-7-carboxylate (CAS 1895711-20-2)
- 5-(Aminomethyl)-4-benzyl-1,2,4-triazole-3-thiol, N-BOC protected (CAS 306935-43-3)
- 2-(3-Fluorophenyl)thiazolidine (CAS 67086-83-3)
- 2-[(1-Methyl-3-piperidinyl)thio]-3-phenylquinolineHydrochloride (CAS 85275-44-1)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com