Atrasentan Impurity 151 CAS 1058403-94-3
| CAS No. | 1058403-94-3 |
| Molecular Formula | C38H56N2O6 |
| Molecular Weight | 636.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Atrasentan Impurity 151 (C38H56N2O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 636.87 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Atrasentan Impurity 151 (CAS 1058403-94-3) is a certified pharmaceutical impurity reference standard with the molecular formula C38H56N2O6 and a molecular weight of 636.87 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C38H56N2O6 |
| Molecular Weight | 636.87 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 107 (CAS 1059052-14-0)
- Atrasentan Impurity 160 (CAS 1059043-98-9)
- Atrasentan Impurity 47 (CAS 1059052-54-8)
- Atrasentan Impurity 61 (CAS 1140455-09-9)
- Atrasentan Impurity 69 (CAS 1058350-12-1)
- Atrasentan Impurity 89 (CAS 1059043-39-8)
- Atrasentan Impurity 93 (CAS 1059043-47-8)
- Atrasentan Impurity 76 (CAS 1058551-13-5)
Recommended Standards
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- Lopinavir-d8 (CAS 224729-35-4)
- Haloperidol impurity 25 (CAS 150214-94-1)
- Diphenhydramine impurity 18 (CAS 150556-79-9)
- Azilsartan Impurity 86 (CAS 2117636-55-0)
- 2-(1h-Imidazol-1-yl)-1-(4-propylphenyl)ethan-1-ol (CAS 1225794-77-3)
- (E)-3-(2-Chloropyridin-4-yl)acrylic acid (CAS 2045276-63-7)
- N-(2,4-Difluorophenyl)-4-nitrobenzenesulfonamide (CAS 737-04-2)
- (1r,2s,5r)-3-(Tert-butoxycarbonyl)-5-(trifluoromethyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid (CAS 1283107-67-4)
- (S)-1,4-Diazabicyclo[4.3.0]nonane (CAS 93643-24-4)
- 5-Amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxamide (CAS 50427-78-6)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
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