(2R)-Methyl 3-{[tert-Butyldimethylsilyl)oxy]}-2-methylpropionate (R)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2-methyl-propanoic Acid Methyl Ester 105859-44-7 CAS 105859-44-7

Purity 97%+In StockPharmaceutical Standards
CAS No.105859-44-7
Molecular FormulaC11H24O3Si
Molecular Weight232.39 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2R)-Methyl 3-{[tert-Butyldimethylsilyl)oxy]}-2-methylpropionate (R)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2-methyl-propanoic Acid Methyl Ester 105859-44-7 CAS 105859-44-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 232.39 g/mol gives (2R)-Methyl 3-{[tert-Butyldimethylsilyl)oxy]}-2-methylpropionate (R)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2-methyl-propanoic Acid Methyl Ester 105859-44-7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(2R)-Methyl 3-{[tert-Butyldimethylsilyl)oxy]}-2-methylpropionate (R)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2-methyl-propanoic Acid Methyl Ester 105859-44-7 (CAS 105859-44-7), molecular formula C11H24O3Si and molecular weight 232.39 g/mol, is a CATO reference standard with documented purity and traceability.

(2R)-Methyl 3-{[tert-Butyldimethylsilyl)oxy]}-2-methylpropionate (R)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2-methyl-propanoic Acid Methyl Ester 105859-44-7 (C11H24O3Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H24O3Si
Molecular Weight232.39 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1987

Recommended Standards

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