Atrasentan Impurity 172 CAS 1059051-96-5
| CAS No. | 1059051-96-5 |
| Molecular Formula | C35H50N2O6 |
| Molecular Weight | 594.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Atrasentan Impurity 172.
Atrasentan Impurity 172 (CAS 1059051-96-5) is a certified pharmaceutical impurity reference standard with the molecular formula C35H50N2O6 and a molecular weight of 594.79 g/mol.
Atrasentan Impurity 172 (C35H50N2O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Atrasentan Impurity 172 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C35H50N2O6 |
| Molecular Weight | 594.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 100 (CAS 1059043-95-6)
- Atrasentan Impurity 102 (CAS 1059052-05-9)
- Atrasentan Impurity 104 (CAS 1059052-11-7)
- Atrasentan Impurity 106 (CAS 1059052-53-7)
- Atrasentan Impurity 115 (CAS 1073836-98-2)
- Atrasentan Impurity 142 (CAS 1058349-25-9)
- Atrasentan Impurity 170 (CAS 1059051-92-1)
- Atrasentan Impurity 176 (CAS 1059051-99-8)
Recommended Standards
- Atrasentan Impurity 45 (CAS 1059044-82-4)
- Atrasentan Impurity 49 (CAS 1059056-95-9)
- Atrasentan Impurity 70 (CAS 1058349-20-4)
- Atrasentan Impurity 95 (CAS 1059043-53-6)
- Clavulanate Potassium EP Impurity B (CAS 96681-85-5)
- Azilsartan Impurity 3 (CAS CATO-C4X-10963)
- Rimegepant Impurity 100 (CAS CATO-C4X-2487100)
- 5H,6H,7H,8H-Imidazo[1,2-a]pyridin-6-ylmethanol (CAS 1256546-79-8)
- 4-Hydroxy-3,6-dimethyl-2H-pyran-2-one (CAS 5192-62-1)
- 2-Amino-5-(aminomethyl)-4-(difluoromethyl)nicotinonitrile (CAS 1805269-55-9)
- 1'-(Cyclopropylmethyl)-1'H-spiro[piperidine-4,4'-quinolin]-2'(3'H)-one (CAS 1422135-58-7)
- 2-Chloro-3-{4-[5-(4-chlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}-1,4-dihydronaphthalene-1,4-dione (CAS 1030937-43-9)
- 3-(2-Bromo-5-iodophenyl)propanenitrile (CAS 1806586-27-5)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
Why CATO?
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