6-Chloro-8-(2-methoxypropan-2-yl)imidazo[1,2-b]pyridazine CAS 105977-09-1

Purity 97%+In StockPharmaceutical Standards
CAS No.105977-09-1
Molecular FormulaC10H12ClN3O
Molecular Weight225.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Chloro-8-(2-methoxypropan-2-yl)imidazo[1,2-b]pyridazine CAS 105977-09-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-8-(2-methoxypropan-2-yl)imidazo[1,2-b]pyridazine.

6-Chloro-8-(2-methoxypropan-2-yl)imidazo[1,2-b]pyridazine (CAS 105977-09-1) is a high-purity analytical reference standard with the molecular formula C10H12ClN3O and a molecular weight of 225.67 g/mol.

The molecular framework of 6-Chloro-8-(2-methoxypropan-2-yl)imidazo[1,2-b]pyridazine (C10H12ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Chloro-8-(2-methoxypropan-2-yl)imidazo[1,2-b]pyridazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H12ClN3O
Molecular Weight225.67 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms3

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