2-(3,5-Bis(trifluoromethyl)phenyl)piperazine CAS 1060807-69-3
| CAS No. | 1060807-69-3 |
| Molecular Formula | C12H12F6N2 |
| Molecular Weight | 298.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 2-(3,5-Bis(trifluoromethyl)phenyl)piperazine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 298.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-(3,5-Bis(trifluoromethyl)phenyl)piperazine (CAS 1060807-69-3), molecular formula C12H12F6N2 and molecular weight 298.23 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(3,5-Bis(trifluoromethyl)phenyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12F6N2 |
| Molecular Weight | 298.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 1-(3,5-Bis(trifluoromethyl)phenyl)piperazine (CAS 16172-96-6)
- Ethyl2-(((trifluoromethyl)sulfonyl)oxy)benzoate (CAS 179538-97-7)
- (R)-2-(4-(((Trifluoromethyl)sulfonyl)oxy)phenyl)propanoic acid (CAS 533931-60-1)
- (S)-2-(4-(((trifluoromethyl)sulfonyl)oxy)phenyl)propanoic acid (CAS 533931-72-5)
- Benzyl 2-(((trifluoromethyl)sulfonyl)oxy)acetate (CAS 77902-89-7)
- 2-Methyl-5-(4-trifluoromethyl-phenyl)-furan-3-carboxylic acid ethyl ester (CAS 1011532-19-6)
- Ethyl 1-(3-(trifluoromethyl)benzyl)-1H-pyrazole-4-carboxylate (CAS 1035224-53-3)
- 2-Phenyl-6-(trifluoromethyl)quinoline-4-carbonitrile (CAS 1416439-23-0)
Recommended Standards
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- (4-Fluorophenyl)-[4-(2,2,2-trifluoroethoxy)-phenyl]-methanone (CAS 113674-87-6)
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- 2-Bromo-5-(difluoromethyl)nicotinic acid (CAS 1804702-33-7)
- 2-(3-Cyclopropyl-4-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 937606-50-3)
- 5-Bromo-2-isopropyl-6-methylpyrimidin-4(1H)-one (CAS 70170-03-5)
- 4-(Carboxymethoxy)phenylboronic acid (CAS 1072945-84-6)
- 3,4-Difluoro-5-methylbenzenesulfonamide (CAS 1803812-94-3)
- Thieno[3,2-b]pyridin-3-amine (CAS 120208-33-5)
- Methyl 3-(2-methylpiperazin-1-yl)propanoate dihydrochloride (CAS 1432679-92-9)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
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