6-Amino-2-(trifluoromethyl)nicotinic acid CAS 1060810-75-4
| CAS No. | 1060810-75-4 |
| Molecular Formula | C7H5F3N2O2 |
| Molecular Weight | 206.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Amino-2-(trifluoromethyl)nicotinic acid.
6-Amino-2-(trifluoromethyl)nicotinic acid (CAS 1060810-75-4) is a high-purity analytical reference standard with the molecular formula C7H5F3N2O2 and a molecular weight of 206.12 g/mol.
The molecular framework of 6-Amino-2-(trifluoromethyl)nicotinic acid (C7H5F3N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Amino-2-(trifluoromethyl)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5F3N2O2 |
| Molecular Weight | 206.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 4-Amino-2-(trifluoromethyl)nicotinic acid (CAS 1018678-42-6)
- 4-Amino-6-(trifluoromethyl)pyridine-2-carboxylic Acid (CAS 1060810-73-2)
- 2-Amino-6-(trifluoromethyl)isonicotinic acid (CAS 1060810-74-3)
- 2-Amino-5-nitrobenzotrifluoride (CAS 121-01-7)
- 3-Amino-5-(trifluoromethyl)picolinic acid (CAS 1214370-77-0)
- 2-Amino-4-(trifluoromethyl)nicotinic acid (CAS 1227489-68-0)
- 2-Amino-5-(trifluoromethyl)isonicotinic acid (CAS 1227582-08-2)
- 2-Amino-3-(trifluoromethyl)isonicotinic acid (CAS 1227582-09-3)
Recommended Standards
- 2-Hydroxy-4-(trifluoromethoxy)benzaldehyde (CAS 1071156-25-6)
- 2,4,5-Trifluoro-3-Methoxybenzoic Acid (CAS 11281-65-5)
- 3,4-Dihydroxy-5-(trifluoromethyl)benzaldehyde (CAS 116314-64-8)
- 4-(Difluoromethoxy)-2-fluorobenzoic acid (CAS 1017779-52-0)
- 2,7-Diamino-4-(pyridin-3-yl)-4H-benzo[h]chromene-3-carbonitrile (CAS 1272756-44-1)
- Methyl 4-((N-phenylphenylsulfonamido)methyl)benzoate (CAS 331750-22-2)
- Ethyl (E)-3-((2-methoxyphenyl)amino)acrylate (CAS 115607-78-8)
- 2-{2-[4-(sec-Butyl)phenoxy]ethyl}piperidinehydrochloride (CAS 1220016-45-4)
- Aminophylline (CAS 317-34-0)
- [4-(aminomethyl)-2-fluorophenyl]methanamine (CAS 1017264-58-2)
- N-(4-Acetylphenyl)-1,2,5-thiadiazole-3-carboxamide (CAS 700860-69-1)
- 1-Benzoylanthracene-9,10-dione (CAS 61726-79-2)
- (E)-2-(p-tolyloxy)nicotinaldehyde O-(3,4-dichlorobenzyl) oxime (CAS 478030-92-1)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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