2-(Chloromethyl)-5-(trifluoromethyl)pyrazine CAS 1060812-69-2
| CAS No. | 1060812-69-2 |
| Molecular Formula | C6H4ClF3N2 |
| Molecular Weight | 196.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-(Chloromethyl)-5-(trifluoromethyl)pyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-(Chloromethyl)-5-(trifluoromethyl)pyrazine (CAS 1060812-69-2) is a high-purity analytical reference standard with the molecular formula C6H4ClF3N2 and a molecular weight of 196.56 g/mol.
2-(Chloromethyl)-5-(trifluoromethyl)pyrazine (C6H4ClF3N2) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF3N2 |
| Molecular Weight | 196.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-6-(trifluoromethyl)pyrazine (CAS 1060812-75-0)
- 2-(Chloromethyl)-3-(trifluoromethyl)pyrazine (CAS 1197229-15-4)
- 2-(Chloromethyl)-4-(trifluoromethyl)pyrimidine (CAS 944905-91-3)
- 4-(Chloromethyl)-6-(trifluoromethyl)pyrimidine (CAS 944901-47-7)
- 5-(Chloromethyl)-2-(trifluoromethyl)pyrimidine (CAS 944901-26-2)
- 2-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]pyrimidine (CAS 1009562-63-3)
- 5-(Chloromethyl)-3-pyrazin-2-yl-1,2,4-oxadiazole (CAS 114346-91-7)
- 2-(Chloromethyl)-5-nitrobenzonitrile (CAS 121996-04-1)
Recommended Standards
- 5-Chloro-2-(trifluoromethyl)pyridin-4-amine (CAS 1060810-26-5)
- 5-Chloro-6-(trifluoromethyl)pyridin-3-amine (CAS 102145-83-5)
- 4-Amino-2-chloro-5-(trifluoromethyl)pyridine (CAS 1061358-78-8)
- 5-Chloro-4-(trifluoromethyl)pyridin-3-amine (CAS 1019108-11-2)
- 1-(3-Aminophenyl)-N,N,N-trimethylmethanaminium chloride (CAS 218938-81-9)
- Tetrabutylammonium (p-nitrophenoxide) (CAS 3002-48-0)
- (1R,4R)-Methyl 4-(hydroxymethyl)cyclohexanecarboxylate (CAS 110928-44-4)
- 5-(Tert-butyl) 6-methyl (S)-3,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine-5,6-dicarboxylate (CAS 1820579-36-9)
- 5-Methylimidazo[1,2-a]pyridin-6-amine (CAS 573764-90-6)
- 878617-56-2 1-[(4-Methyl-1,2,5-oxadiazol-3-yl)methyl]piperazine MFCD01346601 (CAS 878617-56-2)
- Sodium 4-methylpiperazine-1-carbodithioate (CAS 5712-49-2)
- 1-Propyl-1,4-diazepane (CAS 3619-74-7)
- 1-(4-Amino-5-fluoro-2-methylphenyl)ethan-1-one (CAS 1260793-22-3)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com