3-(Chloromethyl)-5-(trifluoromethoxy)pyridine CAS 1060815-05-5
| CAS No. | 1060815-05-5 |
| Molecular Formula | C7H5ClF3NO |
| Molecular Weight | 211.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Chloromethyl)-5-(trifluoromethoxy)pyridine is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(Chloromethyl)-5-(trifluoromethoxy)pyridine (CAS 1060815-05-5), molecular formula C7H5ClF3NO and molecular weight 211.57 g/mol, is a CATO reference standard with documented purity and traceability.
3-(Chloromethyl)-5-(trifluoromethoxy)pyridine (C7H5ClF3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(Chloromethyl)-5-(trifluoromethoxy)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF3NO |
| Molecular Weight | 211.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-5-(trifluoromethoxy)pyridine (CAS 1060814-93-8)
- 3-Chloromethyl-2-hydroxy-5-(trifluoromethyl)pyridine (CAS 1227562-08-4)
- 4-Chloromethyl-3-hydroxy-2-(trifluoromethyl)pyridine (CAS 1227562-18-6)
- 4-Chloromethyl-2-hydroxy-6-(trifluoromethyl)pyridine (CAS 1227562-24-4)
- 3-Chloromethyl-6-hydroxy-2-(trifluoromethyl)pyridine (CAS 1227564-73-9)
- 4-Chloromethyl-2-hydroxy-3-(trifluoromethyl)pyridine (CAS 1227565-46-9)
- 3-Chloromethyl-2-hydroxy-4-(trifluoromethyl)pyridine (CAS 1227581-23-8)
- 3-Chloromethyl-2-hydroxy-6-(trifluoromethyl)pyridine (CAS 1227584-78-2)
Recommended Standards
- (6-Chloro-5-(trifluoromethyl)pyridin-3-yl)methanol (CAS 1113049-91-4)
- 2-AMino-4-chloro-5-(trifluoromethyl)phenol (CAS 1060757-37-0)
- 6-Chloro-5-(trifluoromethyl)pyridine-2,3-diamine (CAS 114087-45-5)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1033463-31-8)
- 2-(4-Methyl-3-nitrophenyl)benzo[d]thiazole (CAS 339220-39-2)
- 5-chloro-4-(piperazin-1-yl)pyrimidine dihydrochloride (CAS 1797573-17-1)
- 2-Methyl-2-(4-(trifluoromethoxy)phenyl)propanoic acid (CAS 1260795-43-4)
- Tadalafil Impurity 60 (CAS 1588526-67-3)
- 2-(1-Carboxy-3-methylbutyl)-1,3-dioxo-2,3-dihydro-1h-isoindole-5-carboxylic acid (CAS 131613-54-2)
- 5-Bromo-6-chloro-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 39215-09-3)
- (E)-3-Bromo-4-(4-methoxyphenyl)-4-oxobut-2-enoic acid (CAS 5711-40-0)
- Methyl (S)-4-Boc-piperazine-2-carboxylate (CAS 314741-39-4)
- Daptomycin Impurity 2 (CAS 121869-35-0)
- Retatrutide (CAS 2381089-83-2)
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