4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-α]pyrimidin-3-yl)quinoline CAS 1062368-24-4
| CAS No. | 1062368-24-4 |
| Molecular Formula | C25H22N6 |
| Molecular Weight | 406.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-α]pyrimidin-3-yl)quinoline (CAS 1062368-24-4) is a high-purity analytical reference standard with the molecular formula C25H22N6 and a molecular weight of 406.48 g/mol.
The molecular framework of 4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-α]pyrimidin-3-yl)quinoline (C25H22N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H22N6 |
| Molecular Weight | 406.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 6 |
Related Piperazin Standards
- Ethyl 2-piperazin-1-yl-4-[4-(trifluoromethoxy)phenyl]-1,3-thiazole-5-carboxylate (CAS 887267-70-1)
- N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)pyrazine-2-carboxamide (CAS 925435-54-7)
- 5-((2-Oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl)methylene)thiazolidine-2,4-dione (CAS 1365986-44-2)
- 4-[6-(4-Methyl-piperazin-1-yl)-5-trifluoromethyl-pyridin-3-yl]-benzoic acid methyl ester (CAS 1208081-77-9)
- 3-[6-(4-Methyl-piperazin-1-yl)-5-trifluoromethyl-pyridin-3-yl]-benzoic acid methyl ester (CAS 1311278-77-9)
- 2-((4-(Piperazin-1-yl)phenyl)amino)-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)pyrimidine-4-carboxamide (CAS 943122-71-2)
- Methyl 4-(piperazin-1-yl-N-BOC protected)-6-(trifluoromethyl)quinoline-2-carboxylate (CAS 887267-65-4)
- 4-[6-(4-Methyl-piperazin-1-yl)-5-trifluoromethyl-pyridin-3-yl]-benzoic acid (CAS 1208081-94-0)
Recommended Standards
- Crotonaldehyde, DAIH derivative (CAS 103480-19-9)
- 4-[(E)-2-(4-Methoxy-3-{4-[(Z)-2-(pyridin-4-yl)ethenyl]phenoxy}phenyl)ethenyl]pyridine (CAS 1171924-43-8)
- 1023519-27-8 4-[(2H-1,3-benzodioxol-5-yl)(4-methylpiperazin-1-yl)methyl]-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one MS-11215 (CAS 1023519-27-8)
- 7-(4-Fluorophenyl)-2-(4-phenylpiperazin-1-yl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1242931-70-9)
- 2-Methylquinazolin-8-ol (CAS 167837-55-0)
- 2,6-Difluoro-3-nitropyridin-4-amine (CAS 60186-20-1)
- (2S)-3-methyl-2-[(2,2,2-trifluoroethyl)amino]butanoic acid hydrochloride (CAS 1955474-01-7)
- Dimethyl 2-Bromosuccinate (CAS 760-90-7)
- 5-Fluoro-2-iodobenzamide (CAS 748188-88-7)
- 2-(2-Oxo-2-(pyrrolidin-1-yl)ethoxy)benzamide (CAS 90074-83-2)
- Diethyl ((2,4-dimethoxyphenyl)(hydroxy)methyl)phosphonate (CAS 62002-63-5)
- 2-Hydroxy-1,2-bis(3-phenoxyphenyl)ethanone (CAS 93982-56-0)
- [4-fluoro-3-(2-methoxyphenoxymethyl)phenyl]methanamine (CAS 1016718-24-3)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
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