2-(Hydroxymethyl)thiophene-3-carbonitrile CAS 106449-27-8
| CAS No. | 106449-27-8 |
| Molecular Formula | C6H5NOS |
| Molecular Weight | 139.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(Hydroxymethyl)thiophene-3-carbonitrile (CAS 106449-27-8), molecular formula C6H5NOS and molecular weight 139.17 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(Hydroxymethyl)thiophene-3-carbonitrile (C6H5NOS) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 139.17 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-(Hydroxymethyl)thiophene-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5NOS |
| Molecular Weight | 139.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Hydroxymethyl Standards
- 5-(Hydroxymethyl)thiophene-2-carbonitrile (CAS 172349-09-6)
- 4-(Hydroxymethyl)thiophene-2-carbonitrile (CAS 186552-06-7)
- 5-(Hydroxymethyl)thiophene-3-carbonitrile (CAS 80577-96-4)
- 5-(Hydroxymethyl)-2-methylpyridine 1-oxide (CAS 102074-25-9)
- 2-(Hydroxymethyl)-4-methylpyridine 1-oxide (CAS 102074-61-3)
- 4-(Hydroxymethyl)-3-methylpyridin-2(1H)-one (CAS 1227514-24-0)
- 5-(Hydroxymethyl)-6-methylpyridin-2-ol (CAS 1227594-54-8)
- 3-(Hydroxymethyl)-5-methylpyridin-2-ol (CAS 1227601-70-8)
Recommended Standards
- 4-Ethyl-3-fluorobenzenamine (CAS 1034497-92-1)
- N-methyl taurine (CAS 107-68-6)
- 3-Fluoro-N,4-dimethylaniline (CAS 1021144-10-4)
- 5,6-Dihydro-4H-thieno[2,3-c]pyrrol-4-one (CAS 1078149-76-4)
- Diethyl Decarboxylated Compound (CAS 177838-59-4)
- 2-(2-((4-Fluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246638-38-8)
- 2-Bromo-4-(3-chloropropyl)-1-fluorobenzene (CAS 1057673-36-5)
- Benzyl 6-(hydroxymethyl)-3-azabicyclo[3.1.0]Hexane-3-carboxylate (CAS 1119512-37-6)
- H-Pro-OMe · HCl (CAS 2133-40-6)
- 1-(Tert-butyl) 6-methyl 2-(trifluoromethyl)-1H-indole-1,6-dicarboxylate (CAS 1492900-83-0)
- Nilvadipine (CAS 75530-68-6)
- 2,2'-(((1R,2R)-Cyclohexane-1,2-diyl)bis(methylene))bis(4-methylbenzenesulfonate) (CAS 62208-94-0)
- Ethyl 1-(pyridin-3-ylmethyl)-1H-pyrazole-5-carboxylate (CAS 2250241-82-6)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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