2-(Methylthio)-4-(piperidin-1-yl)pyrimidine-5-carboxylicacid CAS 1065075-58-2
| CAS No. | 1065075-58-2 |
| Molecular Formula | C11H15N3O2S |
| Molecular Weight | 253.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(Methylthio)-4-(piperidin-1-yl)pyrimidine-5-carboxylicacid (C11H15N3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-(Methylthio)-4-(piperidin-1-yl)pyrimidine-5-carboxylicacid (CAS 1065075-58-2) is a high-purity analytical reference standard with the molecular formula C11H15N3O2S and a molecular weight of 253.32 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15N3O2S |
| Molecular Weight | 253.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- Methyl (4-((methylthio)methyl)benzoyl)glycinate (CAS 1097590-34-5)
- 4-(4-(Methylthio)benzamido)butanoic acid (CAS 1098364-72-7)
- 1-(2-(Methylthio)pyrimidin-4-yl)piperidine-3-carboxylic acid (CAS 1261232-03-4)
- 1-(2-(Methylthio)pyrimidin-4-yl)piperidine-4-carboxylic acid (CAS 1261234-57-4)
- 2-Methyl-6-(3-(methylthio)pyrrolidine-1-carbonyl)pyridazin-3(2H)-one (CAS 1797278-46-6)
- 3-(Methylthio)-5-(naphthalen-2-yl)-1,2,4-triazine (CAS 74417-01-9)
- Ethyl 2-(methylthio)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-4-carboxylate (CAS 944901-89-7)
- 2-(Methylthio)benzo[d]thiazole-5-sulfonic acid (CAS 25991-41-7)
Recommended Standards
- 2-(2-Hydroxyphenyl)-5,5-dimethylthiazolidine-4-carboxylic acid (CAS 105149-48-2)
- 4-(Cyclopentylamino)-2-(methylthio)pyrimidine-5-carboxylic acid (CAS 1065075-68-4)
- 1-(2-(Thiophen-3-yl)acetyl)piperidine-4-carboxylic acid (CAS 1042644-32-5)
- n-((1,1-Dioxidotetrahydrothiophen-3-yl)methyl)benzamide (CAS 1090504-61-2)
- 3-(Pyrrolidin-1-ylmethyl)-1H-indole-6-carboxylic acid (CAS 1081114-00-2)
- Methyl 4-[2-(tert-butylamino)imidazo-[1,2-a]pyrimidin-3-yl]benzoate (CAS 1171483-68-3)
- 3-[cyclohexyl(methyl)sulfamoyl]benzoic acid (CAS 554426-45-8)
- Cisatracurium EP Impurity G (CAS 96946-45-1)
- 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-1H-1,2,4-triazole (CAS 339105-82-7)
- Methanesulfonic Acid 2-Benzyloxycarbonylamino-Propyl Ester (CAS 161494-74-2)
- Testosterone Impurity N16 (CAS 24704-84-5)
- Promestriene Impurity 5 (CAS CATO-C4X-22055)
- Propanedioic acid, 2-methyl-, sodium salt (1:2) (CAS 53007-37-7)
- Des-Ala18-Tirzepatide (CAS CATO-CPTD788955)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com