6-Fluoro-8-methylquinolin-4-ol CAS 1065092-74-1
| CAS No. | 1065092-74-1 |
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Fluoro-8-methylquinolin-4-ol (CAS 1065092-74-1) is a high-purity analytical reference standard with the molecular formula C10H8FNO and a molecular weight of 177.18 g/mol.
6-Fluoro-8-methylquinolin-4-ol (C10H8FNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 6-Fluoro-8-methylquinolin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 5-Fluoro-2-(1h-pyrazol-1-yl)aniline (CAS 1006960-35-5)
- 7-Fluoro-2-methylquinazolin-4-amine (CAS 1009036-30-9)
- 3-(3-Fluoro-4-methylphenyl)-3-oxopropanenitrile (CAS 1016770-89-0)
- 6-FLUORO-7-METHOXY-ISOQUINOLINE (CAS 1036711-00-8)
- 8-Fluoro-4-methylisoquinolin-1(2H)-one (CAS 1050203-45-6)
- 7-Fluoro-8-methylquinolin-4-ol (CAS 1065092-79-6)
- 6-Fluoro-8-hydroxy-2-methylquinoline (CAS 1070897-08-3)
- 7-Fluoro-1-methylquinolin-4(1H)-one (CAS 108494-50-4)
Recommended Standards
- 1-(3-Fluorophenyl)-1h-pyrazol-5-amine (CAS 1056999-20-2)
- 1-(2-Fluorophenyl)-1H-pyrazol-5-amine (CAS 1056999-19-9)
- 6-Fluoro-1-methylquinolin-4(1H)-one (CAS 108494-56-0)
- 3-(3-Fluorophenyl)-1H-pyrazol-5-amine (CAS 1028842-99-0)
- 5-Phenoxypyrimidine-2-carbonitrile (CAS 540463-68-1)
- 2-Bromo-3,4-dimethylbenzophenone (CAS 951892-44-7)
- 2-(Tert-butyl)pyrimidin-5-ol (CAS 85929-96-0)
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- 3-(Carbamothioylamino)benzamide (CAS 500865-55-4)
- 4-(5-Iodopentyloxy)benzonitrile (CAS 147983-19-5)
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- 7-Benzothiazolesulfonic acid, 2-[4-[[2-cyano-3-[4-[methyl(2-sulfoethyl)amino]phenyl]-1-oxo-2-propen-1-yl]amino]phenyl]-6-methyl-, sodium salt (CAS 2498-95-5)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
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