2-(thiophen-2-yl)-1,3-oxazole-5-carboxylic acid CAS 106833-80-1
| CAS No. | 106833-80-1 |
| Molecular Formula | C8H5NO3S |
| Molecular Weight | 195.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(thiophen-2-yl)-1,3-oxazole-5-carboxylic acid (CAS 106833-80-1) is a high-purity analytical reference standard with the molecular formula C8H5NO3S and a molecular weight of 195.20 g/mol.
The molecular framework of 2-(thiophen-2-yl)-1,3-oxazole-5-carboxylic acid (C8H5NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5NO3S |
| Molecular Weight | 195.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related thiophen Standards
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- 2-(3-(Thiophen-3-yl)-1,2,4-oxadiazol-5-yl)ethan-1-amine (CAS 1156371-95-7)
- (5-(Thiophen-2-ylmethyl)-1,2,4-oxadiazol-3-yl)methanamine (CAS 1208409-04-4)
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Recommended Standards
- 2-(1H-Pyrazol-4-yl)thiazole-4-carboxylic acid (CAS 1023594-72-0)
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- 1086380-33-7 5-(furan-2-yl)-1,3-thiazole-4-carboxylic acid TS-00296 (CAS 1086380-33-7)
- UDP-a-D-Glucose (CAS 133-89-1)
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- 2-(3-Amino-4H-thieno[3,4-c]pyrazol-2(6H)-yl)-N-(4-fluorobenzyl)acetamide (CAS 1105190-69-9)
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- 3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carbonitrile (CAS 610259-29-5)
- Apigenin 7-O-(2G-rhamnosyl)gentiobioside (CAS 174284-20-9)
- 1-[4-(2-Chloroethoxy)phenyl]-2-phenylethanone 19561-95-6 4'-(2-Chloroethoxy)-2-phenyl-acetophenone Benzyl p-(2-Chloroethoxy)phenyl Ketone (CAS 19561-95-6)
- 4-Nitro-N-(2-(2-phenyl-1H-indol-3-yl)ethyl)benzenesulfonamide (CAS 648894-21-7)
- 2-(5-Fluoro-2-methylphenyl)-4,5-dihydro-1H-imidazole (CAS 266317-42-4)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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