1H-pyrazolo[3,4-b]quinolin-3-amine CAS 106835-44-3
| CAS No. | 106835-44-3 |
| Molecular Formula | C10H8N4 |
| Molecular Weight | 184.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1H-pyrazolo[3,4-b]quinolin-3-amine.
1H-pyrazolo[3,4-b]quinolin-3-amine (CAS 106835-44-3), molecular formula C10H8N4 and molecular weight 184.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1H-pyrazolo[3,4-b]quinolin-3-amine (C10H8N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1H-pyrazolo[3,4-b]quinolin-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8N4 |
| Molecular Weight | 184.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Related H Standards
- 1H-pyrazolo[4,3-c]quinolin-3-amine (CAS 156912-12-8)
- methyl pyrazolo[1,5-a]pyridine-5-carboxylate (CAS 1101120-07-3)
- 4H-Pyrazolo[5,1-c][1,4]oxazine-6-carbonitrile, 3-chloro-6,7-dihydro- (CAS 2121711-49-5)
- Pyrazolo[1,5-a]quinoxalin-4(5H)-one (CAS 114722-60-0)
- 2H-Pyrazolo[3,4-b]quinoxalin-3-amine (CAS 56984-56-6)
- methyl pyrazolo[1,5-a]pyrazine-3-carboxylate (CAS 53902-64-0)
- methyl pyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 331647-95-1)
- Pyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-6(7H)-one (CAS 148191-54-2)
Recommended Standards
- 1-[2-(dimethylamino)ethyl]-1H-1,2,3-triazole-4-carboxylic acid (CAS 1038705-93-9)
- 4-Methyl-[1,2,3]triazolo[1,5-a]quinoxaline (CAS 111339-68-5)
- n-(4-Amino-1,2,5-oxadiazol-3-yl)-2,2-dimethylpropanamide (CAS 1030574-73-2)
- 2-(4-Methyl-1H-pyrazol-1-yl)nicotinonitrile (CAS 1119391-07-9)
- 4-(3-Chloro-4-methylbenzylidene)-2-phenyloxazol-5(4H)-one (CAS 61887-36-3)
- Gibberellin A4 methyl ester (CAS 19124-90-4)
- 4-Iodo-1-methyl-3-nitro-1H-pyrazole-5-carboxylic acid (CAS 1354705-31-9)
- 1-Bromo-2,5-dimethoxy-3,4,6-trimethylbenzene (CAS 69821-05-2)
- 1-((Methylsulfinyl)methyl)-1H-benzo[d][1,2,3]triazole (CAS 304658-62-6)
- 1-(3-((6-Bromopyridin-2-yl)methyl)pyrrolidin-1-yl)-2,2-dimethylpropan-1-one (CAS 1316221-44-9)
- Linezolid -D8 (CAS 1032182-14-1)
- Methyl 2-[(3,4,4-trifluoro-3-butenyl)sulfanyl]acetate (CAS 179947-01-4)
- 5-(2-Chlorophenyl)-N-(2,4-dichlorophenyl)furan-2-carboxamide (CAS 618400-28-5)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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