Ethyl (3-hydroxypyridin-2-yl)carbamate CAS 106840-72-6
| CAS No. | 106840-72-6 |
| Molecular Formula | C8H10N2O3 |
| Molecular Weight | 182.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl (3-hydroxypyridin-2-yl)carbamate (CAS 106840-72-6), molecular formula C8H10N2O3 and molecular weight 182.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl (3-hydroxypyridin-2-yl)carbamate (C8H10N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Ethyl (3-hydroxypyridin-2-yl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O3 |
| Molecular Weight | 182.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- Methyl 2-((3-hydroxypyridin-2-yl)oxy)acetate (CAS 353292-80-5)
- Methyl 2-((5-hydroxypyridin-2-yl)oxy)acetate (CAS 353293-42-2)
- Ethyl 2-(3-hydroxypyridin-2-yl)acetate (CAS 2584-12-5)
- Ethyl 2-(6-hydroxypyridin-3-yl)acetate (CAS 847375-00-2)
- 2-((5-Hydroxypyridin-2-yl)methylene)hydrazine-1-carboximidamide (CAS 50696-27-0)
- ethyl 2-(5-hydroxypyridin-2-yl)acetate (CAS 132807-30-8)
- N-(3-Hydroxypyridin-4-yl)methanesulfonamide (CAS 1243287-60-6)
- N-(5-hydroxypyridin-2-yl)methanesulfonamide (CAS 1243382-11-7)
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