2-Amino-3-(2-fluoro-3-hydroxyphenyl)propanoic acid CAS 1069068-09-2
| CAS No. | 1069068-09-2 |
| Molecular Formula | C9H10FNO3 |
| Molecular Weight | 199.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-3-(2-fluoro-3-hydroxyphenyl)propanoic acid.
2-Amino-3-(2-fluoro-3-hydroxyphenyl)propanoic acid (CAS 1069068-09-2), molecular formula C9H10FNO3 and molecular weight 199.18 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Amino-3-(2-fluoro-3-hydroxyphenyl)propanoic acid (C9H10FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 199.18 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10FNO3 |
| Molecular Weight | 199.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- (3S)-3-Amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid (CAS 1027335-64-3)
- Methyl 4-amino-2-fluoro-5-methoxybenzoate (CAS 1137869-87-4)
- 6-Amino-3-ethoxy-2-fluorobenzoic acid (CAS 1178813-12-1)
- Methyl 2-amino-3-fluoro-4-methoxybenzoate (CAS 1180497-48-6)
- (R)-2-amino-3-(2-fluoro-4-hydroxyphenyl)propanoic acid hydrochloride (CAS 1241679-19-5)
- methyl 2-amino-5-fluoro-3-methoxybenzoate (CAS 1247936-83-9)
- Ethyl 2-amino-4-fluoro-5-hydroxybenzoate (CAS 1248820-25-8)
- 2-Amino-5-ethoxy-4-fluorobenzoic acid (CAS 1249449-47-5)
Recommended Standards
- 2,4-Difluorobenzoyl isothiocyanate (CAS 105534-76-7)
- 1-Ethyl-2-fluoro-4-methoxy-5-nitrobenzene (CAS 1089282-52-9)
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- 1-Ethoxy-5-fluoro-4-methyl-2-nitrobenzene (CAS 1089283-14-6)
- 1-(2-Fluoro-3-methoxyphenyl)-N-methylmethanamine (CAS 921219-95-6)
- 4-(2,3-Dihydrobenzofuran-5-yl)butan-1-ol (CAS 1517873-49-2)
- 3-(4-Chlorophenyl)-1,3-thiazolidin-4-one (CAS 338417-75-7)
- 2-(2-Bromophenyl)-2-hydroxyacetonitrile (CAS 52923-21-4)
- 6-Fluoro-7-hydroxy-4-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS 2378746-11-1)
- Camfetamine Hydrochloride (CAS 39628-11-0)
- JTP-1048196 (CAS 55377-56-5)
- 3-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy]-1,2-propanediol (CAS 86491-83-0)
- 4,4'-(1,10-Phenanthroline-2,9-diyl)dibenzaldehyde (CAS 120085-99-6)
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