2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-(trifluoromethoxy)-1H-indole CAS 1072813-63-8
| CAS No. | 1072813-63-8 |
| Molecular Formula | C15H17BF3NO3 |
| Molecular Weight | 327.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-(trifluoromethoxy)-1H-indole (C15H17BF3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-(trifluoromethoxy)-1H-indole (CAS 1072813-63-8), molecular formula C15H17BF3NO3 and molecular weight 327.11 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H17BF3NO3 |
| Molecular Weight | 327.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Tetramethyl Standards
- Benzyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carboxylate (CAS 1233525-94-4)
- benzyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole-1-carboxylate (CAS 1256360-11-8)
- 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-2-azabicyclo[2.2.2]octane (CAS 2246437-55-6)
- 1,1,3,3-tetramethyl-2,3-dihydro-1H-inden-5-ol (CAS 53718-26-6)
- 1,1,3,3-Tetramethyl-1,3-bis(3,3,3-trifluoropropyl)disiloxane (CAS 690-56-2)
- 2,2,6,6-Tetramethyl-4-(4'-toluenesulfonate)piperidinooxyl (CAS 42495-21-6)
- 1-{[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl}piperidine-4-carbonitrile (CAS 1206641-46-4)
- N-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)propane-2-sulfonamide (CAS 1083326-57-1)
Recommended Standards
- 1-(3-Bromo-4-methoxyphenyl)-3-(2,2,2-trifluoroethyl)urea (CAS 1333862-49-9)
- 4-(2-Bromo-4-fluorophenyl)-1,1,1-trifluoro-4-methyl-2-pentanone (CAS 1198785-52-2)
- 2-(4-Bromo-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanoic acid (CAS 1006320-26-8)
- 2-Methoxy-5-(pentafluorosulfur)benzyl bromide (CAS 1240257-53-7)
- 1-(2,3-Dihydro-1h-inden-2-yl)-2,2,2-trifluoroethan-1-one (CAS 1085493-39-5)
- 3-Amino-4-chloro-N-(2-chlorophenyl)benzenesulfonamide (CAS 325724-69-4)
- 3-(2-Fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one (CAS 638139-53-4)
- 1-Boc-3-[(Dimethylamino)methylene]-4-oxopiperidine (CAS 157327-41-8)
- 7-Bromo-1,3-dihydrofuro[3,4-c]pyridin-4-amine (CAS 1902982-92-6)
- 4-Bromo-N-ethylbenzenesulfonamide (CAS 1984-25-4)
- Acetyl 2-[(2-Formamide-1,6-dihydro-6-chloro-9H-purin-9yl)methoxy]ethyl Ester (CAS 1346598-89-7)
- 4-(4-Chlorophenoxy)-6-(((4-chlorophenyl)thio)methyl)-2-phenylpyrimidine (CAS 303147-12-8)
- 8-Amino-6-methyl-3,4-dihydroquinolin-2(1H)-one (CAS 1243250-09-0)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com