(1-(6-Chloropyrimidin-4-yl)-1H-pyrazol-4-yl)boronic acid CAS 1072945-81-3
| CAS No. | 1072945-81-3 |
| Molecular Formula | C7H6BClN4O2 |
| Molecular Weight | 224.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(1-(6-Chloropyrimidin-4-yl)-1H-pyrazol-4-yl)boronic acid (CAS 1072945-81-3), molecular formula C7H6BClN4O2 and molecular weight 224.41 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (1-(6-Chloropyrimidin-4-yl)-1H-pyrazol-4-yl)boronic acid (C7H6BClN4O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.5, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 224.41 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (1-(6-Chloropyrimidin-4-yl)-1H-pyrazol-4-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6BClN4O2 |
| Molecular Weight | 224.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloropyrimidin Standards
- (1-(5-Chloropyrimidin-2-yl)-1H-pyrazol-4-yl)boronic acid (CAS 2225169-84-4)
- (4-(2-Chloropyrimidin-4-yl)furan-2-yl)boronic acid (CAS 2225177-86-4)
- 3-(2-Chloropyrimidin-4-yl)bicyclo[1.1.1]Pentane-1-carboxylic acid (CAS 2167383-15-3)
- 6-(2-chloropyrimidin-5-yl)hex-5-ynoic acid (CAS 2643500-61-0)
- 4-(2-Chloropyrimidin-4-yl)thiophene-2-carbaldehyde (CAS 937273-39-7)
- 3-(2-Chloropyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octane (CAS 777836-02-9)
- 1-(2-Chloropyrimidin-4-yl)piperidine-4-carbonitrile (CAS 954226-84-7)
- 1-(6-Chloropyrimidin-4-yl)piperidine-4-carbonitrile (CAS 945896-87-7)
Recommended Standards
- 3,5-Dimethoxy-3,5-dimethyl-2,6-dioxa-3,5-disilaheptane (CAS 18297-79-5)
- Tert-butyl((3-ethynylcyclobutyl)methoxy)dimethylsilane (CAS 162039-21-6)
- (R,S)-1,2-diamino-1,2-diphenylethane 951-87-1 meso-(1R,2S)-1,2-diphenylethylenediamine meso-1,2-diphenylethylenediamine meso-1,2-diphenylethylenediamine 98% (CAS 951-87-1)
- Tert-butyl(((1s,3s)-3-ethynylcyclobutyl)methoxy)dimethylsilane (CAS 163634-18-2)
- 2,4-Dibromo-3,6-dimethoxyaniline (CAS 1160574-43-5)
- 3-(n-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)-n-methylsulfamoyl)benzoic acid (CAS 556007-00-2)
- 3,4,6-Trifluoropyridin-2-amine (CAS 63489-59-8)
- 5-Bromo-2-chloro-N-(2,2-dimethoxyethyl)benzamide (CAS 477772-67-1)
- (1R,3R)-Methyl 3-aminocyclopentanecarboxylate hydrochloride (CAS 222530-45-2)
- 6-(Bromomethyl)-1-naphthonitrile (CAS 81940-37-6)
- 2-(4-Methoxyphenyl)-1H-benzo[d]imidazole-5-carboxamide (CAS 178970-16-6)
- Eldecalcitol Impurity 21 (CAS 1809782-41-9)
- 1-Methyl-1H-imidazol-2-amine hydrochloride (CAS 1450-94-8)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
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