5-Chloro-2-(2,2,2-trifluoroethoxy)benzoic acid CAS 1075243-52-5
| CAS No. | 1075243-52-5 |
| Molecular Formula | C9H6ClF3O3 |
| Molecular Weight | 254.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Chloro-2-(2,2,2-trifluoroethoxy)benzoic acid (C9H6ClF3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Chloro-2-(2,2,2-trifluoroethoxy)benzoic acid (CAS 1075243-52-5) is a high-purity analytical reference standard with the molecular formula C9H6ClF3O3 and a molecular weight of 254.59 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-2-(2,2,2-trifluoroethoxy)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6ClF3O3 |
| Molecular Weight | 254.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
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- ((1S,5R)-3-oxabicyclo[3.1.0]Hexan-1-yl)methanol (CAS 2306255-58-1)
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