Atracurium Impurity 82 CAS 1075726-70-3
| CAS No. | 1075726-70-3 |
| Molecular Formula | C27H37NO6 |
| Molecular Weight | 471.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Atracurium Impurity 82 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Atracurium Impurity 82 (CAS 1075726-70-3) is a certified pharmaceutical impurity reference standard with the molecular formula C27H37NO6 and a molecular weight of 471.59 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Atracurium Impurity 82 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 471.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H37NO6 |
| Molecular Weight | 471.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 1 |
Related Atracurium Standards
- Atracurium Impurity 115 (CAS CATO-C4X-1850115)
- Atracurium Impurity 111 (CAS CATO-C4X-1850111)
- Atracurium Impurity 7 (CAS 1100676-15-0)
- Atracurium Impurity 75 (CAS CATO-C4X-185075)
- Atracurium Impurity 118 (CAS 24734-71-2)
- Atracurium impurity 103 (CAS 872807-64-2)
- Atracurium Impurity 105 (CAS CATO-C4X-1850105)
- Atracurium EP Impurity C (CAS CATO-C4X-185063)
Recommended Standards
- Revefenacin Impurity 23 (CAS CATO-C4X-203123)
- Cefathiamidine Impurity 12 (CAS CATO-C4X-133712)
- Vardenafil Acetyl-d5 Analogue (CAS 1330171-51-1)
- Tamsulosin Impurity 65 (CAS CATO-C4X-118765)
- Vonoprazan Impurity 166 (CAS CATO-C4X-1020166)
- Haloperidol Decanoate EP Impurity C (CAS CATO-C4X-146135)
- Etoricoxib Impurity 85 (CAS CATO-C4X-108085)
- 1,4,5,8-Tetraamino-2,7-bis(3-octylphenoxy)anthracene-9,10-dione (CAS 88623-53-4)
- 123740-94-3 2-(4-n-Butylphenyl)-5-n-propyl-pyrimidine MFCD00799382 (CAS 123740-94-3)
- (4Z)-1-(4,5-Dihydro-1,3-thiazol-2-yl)-3-methyl-4-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-4,5-dihydro-1H-pyrazol-5-one (CAS 338402-56-5)
- 5-Bromo-1H-indazole-4-carboxylic acid (CAS 750586-03-9)
- Levodopa Impurity 27 (CAS CATO-C4X-167627)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethoxy)pyridine-4-carboxylic acid (CAS 1804712-26-2)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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