1-Bromo-3-fluoroisoquinoline CAS 1076-36-4
| CAS No. | 1076-36-4 |
| Molecular Formula | C9H5BrFN |
| Molecular Weight | 226.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Bromo-3-fluoroisoquinoline (CAS 1076-36-4) is a high-purity analytical reference standard with the molecular formula C9H5BrFN and a molecular weight of 226.05 g/mol.
Based on its molecular formula C9H5BrFN, 1-Bromo-3-fluoroisoquinoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 226.05 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Bromo-3-fluoroisoquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5BrFN |
| Molecular Weight | 226.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-7-fluoroquinoline (CAS 1070879-29-6)
- 5-Bromo-6-fluoroquinoline (CAS 107224-21-5)
- 5-Bromo-8-fluoroquinoline (CAS 1133115-78-2)
- 1-Bromo-6-fluoroisoquinoline (CAS 1196151-59-3)
- 1-Bromo-7-fluoroisoquinoline (CAS 1207448-24-5)
- 1-Bromo-5-fluoroisoquinoline (CAS 1207448-30-3)
- 5-Bromo-7-fluoroquinoline (CAS 1239462-97-5)
- 5-Bromo-6-fluoroisoquinoline (CAS 1239463-43-4)
Recommended Standards
- 2-(2,4-Dichlorophenyl)-2,2-difluoroethan-1-amine (CAS 1004284-28-9)
- 5-Bromo-2-carboxy-3-fluoropyridine 5-Bromo-3-fluoropicolinic acid 5-bromo-3-fluoropyridine-2-carboxylic acid 669066-91-5 (CAS 669066-91-5)
- 1-BROMO-4-FLUORO-3-NITROBENZENE 2-FLUORO-5-BROMONITROBENZENE 364-73-8 4-BROMO-1-FLUORO-2-NITROBENZENE 5-BROMO-2-FLUORONITROBENZENE BC002059 BENZENE, 4-BROMO-1-FLUORO-2-NITRO- (CAS 364-73-8)
- methyl 5-bromo-4-fluoro-1H-pyrrole-3-carboxylate (CAS 2092695-82-2)
- (3AS,4R,6S,7R,7aR)-6-(ethylthio)-4-(hydroxymethyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-7-ol (CAS 172146-95-1)
- tributyl(3,3,3-trifluoroprop-1-ynyl)stannane (CAS 64185-12-2)
- 2-Bromo-N-(3,4-dihydroxyphenethyl)propanamide (CAS 862673-06-1)
- n-(1-(2-Fluorophenyl)ethyl)-2-methylpropan-1-amine (CAS 1019628-94-4)
- (2S,3R,4R,5S,6R)-2-(3-bromophenyl)-6-(hydroxymethyl)oxane-3,4,5-triol (CAS 655237-65-3)
- 2-(4-Fluorophenyl)pyrrolidine (CAS 72216-06-9)
- (2-Cyclopropyl-5-fluoropyridin-4-yl)boronic acid (CAS 2225174-24-1)
- 2-((5-Nitrofuran-2-yl)methoxy)ethyl benzoate (CAS 88796-66-1)
- N-(cyanomethyl)-4-methoxybenzamide (CAS 22192-84-3)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com