2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]thio]-5-(tert-butyldimethylsilyloxy)-1H-benzimidazole CAS 1076198-62-3
| CAS No. | 1076198-62-3 |
| Molecular Formula | C22H28F3N3O2SSi |
| Molecular Weight | 483.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]thio]-5-(tert-butyldimethylsilyloxy)-1H-benzimidazole is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]thio]-5-(tert-butyldimethylsilyloxy)-1H-benzimidazole (CAS 1076198-62-3), a certified reference material (molecular formula C22H28F3N3O2SSi, MW 483.62 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]thio]-5-(tert-butyldimethylsilyloxy)-1H-benzimidazole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 483.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]thio]-5-(tert-butyldimethylsilyloxy)-1H-benzimidazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28F3N3O2SSi |
| Molecular Weight | 483.62 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- [2,5-Bis(2,2,2-trifluoroethoxy)phenyl]formamido 2-chlorobenzoate (CAS 338394-88-0)
- 6-(2,2,2-Trifluoroethoxy)-N-[2-[[[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]carbonyl]amino]ethyl]nicotinamide (CAS 1003576-00-8)
- 2,5-Bis(2,2,2-trifluoroethoxy)-N'-(3-(trifluoromethyl)benzoyl)benzohydrazide (CAS 477872-45-0)
- 2,5-Bis(2,2,2-trifluoroethoxy)-N-((3-(trifluoromethyl)benzoyl)oxy)benzamide (CAS 320418-87-9)
- 338394-12-0 4-[2,5-bis(2,2,2-trifluoroethoxy)benzoyl]-N-phenyltetrahydro-1(2H)-pyrazinecarboxamide KS-000033FX (CAS 338394-12-0)
- [2,5-Bis(2,2,2-trifluoroethoxy)phenyl]formamido N-[3-(trifluoromethyl)phenyl]carbamate (CAS 338395-11-2)
- 2,5-Bis(2,2,2-trifluoroethoxy)-N-(2-{[3-(trifluoromethyl)phenyl]formamido}ethyl)benzamide (CAS 338404-44-7)
- 5-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-1-(4-methylphenyl)-1H-1,2,4-triazole (CAS 400081-38-1)
Recommended Standards
- 2-((5-Benzyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-phenylthiazol-2-yl)acetamide (CAS 332922-41-5)
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- Alectinib impurity 24 (CAS 1256585-32-6)
- 1-Morpholino-2-((5-morpholino-4-tosylthiazol-2-yl)thio)ethan-1-one (CAS 874594-15-7)
- 3-(n-Cyclopropyl-2,2,2-trifluoroacetamido)propanoic acid (CAS 1178418-17-1)
- 4-(Piperazin-1-yl)indoline (CAS 105685-18-5)
- 7-(5,7-Dimethyl-2-oxoindolin-3-ylidene)-3-phenyl-3,4-dihydro-2H-thiazolo[3,2-a][1,3,5]triazin-6(7H)-one (CAS 840476-99-5)
- 4-Bromopyrazole-3-carbonitrile (CAS 288246-16-2)
- 3,3'-Dichlorobenzidine-d6 (CAS 93951-91-8)
- N-(4-Chloro-1,3-benzothiazol-2-yl)-N-methylglycine (CAS 1353000-10-8)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((2,3,5,6-tetramethylphenyl)thio)acetamide (CAS 1012219-42-9)
- 3-(5-bromothiophen-2-yl)-5-(chloromethyl)-1,2,4-oxadiazole (CAS 1306605-39-9)
- 2-(5-Cyclopentyl-1,2,4-oxadiazol-3-yl)morpholine hydrochloride (CAS 1707602-55-8)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
Why CATO?
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