Mivacurium Chloride Impurity 8 (R-R isomer) CAS 107740-65-8
| CAS No. | 107740-65-8 |
| Molecular Formula | C58H80N2O14 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Mivacurium Chloride Impurity 8 (R-R isomer) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Mivacurium Chloride Impurity 8 (R-R isomer) (CAS 107740-65-8, C58H80N2O14Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Mivacurium Chloride Impurity 8 (R-R isomer) (C58H80N2O14Cl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.5, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 1064.73 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C58H80N2O14 2*Cl |
| Molecular Weight | 1064.73 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Mivacurium Standards
- Mivacurium Chloride Impurity 5 (CAS 1026602-92-5)
- Mivacurium Chloride Impurity 21 (CAS 104758-47-6)
- Mivacurium chloride Impurity 25 (CAS 104758-49-8（free base）)
- Mivacurium Chloride Impurity 7 (S-S isomer) (CAS 104758-51-2)
- Mivacurium (CAS 106791-40-6)
- Mivacurium Chloride (Mixture of Diastereomers) (CAS 106861-44-3)
- Mivacurium Chloride Impurity 6 (R-S isomer) (CAS 107740-63-6)
- Mivacurium Chloride Impurity 14 (CAS 107740-64-7)
Recommended Standards
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- (S)-3-(5-bromo-2-chlorophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 1993341-59-5)
- Ethyl 6-(phenylcarbamoyl)-4-(trifluoromethyl)pyridine-2-carboxylate (CAS 1210182-96-9)
- 2-Amino-3-benzyloxypyridine-5-boronic acid pinacol ester, >97% (CAS 756520-57-7)
- [Plus-β-Ala28]-Semaglutide (CAS CATO-C4X-2226221)
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