Zafirlukast Nitroindole Genotoxic Impurity CRS CAS 107754-15-4
| CAS No. | 107754-15-4 |
| Molecular Formula | C19H18N2O5 |
| Molecular Weight | 354.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Zafirlukast Nitroindole Genotoxic Impurity CRS.
Zafirlukast Nitroindole Genotoxic Impurity CRS (CAS 107754-15-4), molecular formula C19H18N2O5 and molecular weight 354.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Zafirlukast Nitroindole Genotoxic Impurity CRS (C19H18N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Zafirlukast Nitroindole Genotoxic Impurity CRS meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18N2O5 |
| Molecular Weight | 354.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Zafirlukast Standards
- Zafirlukast Impurity 3 (CAS 107754-14-3)
- Zafirlukast Methyl Ester Impurity (CAS 107754-19-8)
- Zafirlukast M1 Metabolite (CAS 219583-10-5)
- Zafirlukast m-Tolyl Isomer (CAS 1159195-69-3)
- Zafirlukast p-Tolyl Isomer (CAS 1159195-70-6)
- Zafirlukast (CAS 107753-78-6)
- Zafirlukast M5 MetaboliteDISCONTINUED (CAS 219582-82-8)
Recommended Standards
- Ethyl 4-((3-(2-hydroxy-4-methoxyphenyl)-1H-pyrazol-4-yl)oxy)benzoate (CAS 1010869-14-3)
- 6-(4-Fluorophenyl)-2-((3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)methyl)pyridazin-3(2H)-one (CAS 1105196-45-9)
- Methyl 2-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)formamido]-2-phenylacetate (CAS 1008710-08-4)
- Methyl 6-((5-cyanopyrazin-2-yl)amino)-4-(methyl(3-methyloxetan-3-yl)amino)nicotinate (CAS 1137476-04-0)
- 5-Amino-N-(4-fluorophenyl)-1,3,4-thiadiazole-2-acetamide (CAS 946743-23-3)
- 5-Oxo-1-(1-phenyl-ethyl)-pyrrolidine-3-carboxylic acid ethyl ester (CAS 96449-84-2)
- 12(Z),15(Z)-Heneicosadienoic acid (CAS 191545-08-1)
- 5-Bromo-2-((trifluoromethyl)thio)pyrimidine (CAS 2091632-09-4)
- 2-(4-Nitro-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetic acid (CAS 1006957-15-8)
- L-741,742 Hydrochloride (CAS 874882-93-6)
- 7-Bromo-6-chloro-2-methylquinazolin-4-amine (CAS 2384812-42-2)
- 5-Chloro-4-{[(2,4-dimethylphenyl)sulfanyl]methyl}-1-methyl-3-phenyl-1H-pyrazole (CAS 318234-14-9)
- Methyl 5,6,7,8-tetrahydroimidazo[1,5-α]pyridine-6-carboxylate (CAS 139183-91-8)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com