(2R,3R,4S,5R)-2-(6-Amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate CAS 1078724-45-4
| CAS No. | 1078724-45-4 |
| Molecular Formula | C10H12ClN5O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2R,3R,4S,5R)-2-(6-Amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2R,3R,4S,5R)-2-(6-Amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate (CAS 1078724-45-4), molecular formula C10H12ClN5O4H2O and molecular weight 319.70 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H12ClN5O4H2O, (2R,3R,4S,5R)-2-(6-Amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 319.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2R,3R,4S,5R)-2-(6-Amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN5O4 H2O |
| Molecular Weight | 319.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
- 6-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4(2H)-one (CAS 134791-37-0)
- (S)-2-(3-Oxo-1-phenyl-3-(4-(trifluoromethyl)phenyl)propyl)malonic acid (CAS 1410101-91-5)
- 4,5-Dimethylthiazole-2-carboxylic Acid (CAS 79312-41-7)
- 4-Bromo-2-(hydroxymethyl)benzoic Acid (CAS 670256-21-0)
- (Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) (CAS 122018-58-0)
- 5-Bromo-2-hydroxy-4-methylacetophenone (CAS 50342-17-1)
- N-Formyl-4-iodo-l-phenylalanine (CAS 52721-77-4)
- 4-Methyl-2-(methylthio)-6-(trifluoromethyl)pyrimidine (CAS 62772-91-2)
- (5-Methylthiophen-2-yl)(tetrahydro-2h-pyran-4-yl)methanamine (CAS 1340276-48-3)
- Semaglutide Impurity 122 (CAS CATO-C4X-2226122)
Why CATO?
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