3-Fluoro-4-(hydroxymethyl)phenylboronic Acid Pinacol Ester CAS 1082066-29-2
| CAS No. | 1082066-29-2 |
| Molecular Formula | C13H18BFO3 |
| Molecular Weight | 252.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Fluoro-4-(hydroxymethyl)phenylboronic Acid Pinacol Ester (C13H18BFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 3-Fluoro-4-(hydroxymethyl)phenylboronic Acid Pinacol Ester (CAS 1082066-29-2), a certified reference material (molecular formula C13H18BFO3, MW 252.09 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Fluoro-4-(hydroxymethyl)phenylboronic Acid Pinacol Ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H18BFO3 |
| Molecular Weight | 252.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Fluoro Standards
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- [4-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol (CAS 1333264-06-4)
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- (5-Fluoro-2-((4-methylpiperazin-1-yl)methyl)phenyl)boronic acid (CAS 1333387-98-6)
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Why CATO?
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