1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol CAS 1082367-11-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1082367-11-0
Molecular FormulaC13H12N4S
Molecular Weight256.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol CAS 1082367-11-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 256.33 g/mol gives 1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1082367-11-0), molecular formula C13H12N4S and molecular weight 256.33 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (C13H12N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2,4-Dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H12N4S
Molecular Weight256.33 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms4
Sulfur Atoms1

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