Gabapentin Impurity 8 HCl CAS 1083246-63-2
| CAS No. | 1083246-63-2 |
| Molecular Formula | C18H32N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Gabapentin Impurity 8 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Gabapentin Impurity 8 HCl (CAS 1083246-63-2), a pharmacopoeial impurity reference standard (molecular formula C18H32N2O3HCl, MW 360.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Gabapentin Impurity 8 HCl is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H32N2O3 HCl |
| Molecular Weight | 360.92 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Gabapentin Standards
- Gabapentin EP Impurity D (CAS 1076198-17-8)
- Gabapentin Impurity 13 (CAS 1130-32-1)
- Gabapentin-d4 (CAS 1185039-20-6)
- Gabapentin Impurity 16 (CAS 1281568-83-9)
- Gabapentin EP Impurity B (CAS 133481-09-1)
- Gabapentin EP Impurity B Potassium Salt (CAS 133481-12-6)
- Gabapentin-d6 (CAS 1346600-67-6)
- Ethyl gabapentin ester, >98% (CAS 138799-97-0)
Recommended Standards
- Imatinib Impurity 79 (CAS CATO-C4X-106879)
- Gadobutrol impurity 160 (CAS CATO-C4X-2120160)
- Vitamin K1 Impurity 59 (CAS CATO-C4X-220759)
- 6-(4-Methylbenzyl)isothiazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione (CAS 1326942-95-3)
- 3-(6-Nitrobenzo[d][1,3]dioxol-5-yl)oxazolidin-2-one (CAS 936076-13-0)
- Selumetinib Impurity 6 (CAS CATO-C4X-30536)
- Barium 2-methoxyethan-1-olate (CAS 115503-13-4)
- 2-Bromo-4-(cyclopentyloxy)-5-methoxybenzaldehyde (CAS 692281-23-5)
- 4-(4-Chloro-3-(trifluoromethyl)phenyl)-4-oxobutanoic acid (CAS 75381-63-4)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com