tert-Butyl 2-amino-4,5-dimethylthiophene-3-carboxylate CAS 108354-76-3
| CAS No. | 108354-76-3 |
| Molecular Formula | C11H17NO2S |
| Molecular Weight | 227.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl 2-amino-4,5-dimethylthiophene-3-carboxylate (C11H17NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies tert-Butyl 2-amino-4,5-dimethylthiophene-3-carboxylate (CAS 108354-76-3), a certified reference material (molecular formula C11H17NO2S, MW 227.32 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H17NO2S |
| Molecular Weight | 227.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- 4-(Toluene-4-sulfonyl)butylamine (CAS 1018300-58-7)
- 4-(tert-Butyl)-N-methylbenzenesulfonamide (CAS 111370-28-6)
- N,n-diphenylethanethioamide (CAS 100363-24-4)
- 2-([(2,3-Dimethoxyphenyl)methyl]-sulfanyl)ethan-1-amine (CAS 1147093-47-7)
- Ethyl 5-amino-1,2,3-oxadiazole-4-carboxylate (CAS 371201-27-3)
- Tert-butyl 3-(((2-methoxyethyl)amino)methyl)pyrrolidine-1-carboxylate (CAS 887591-57-3)
- 625-88-7 2,5-Diiodothiophene Thiophene, 2,5-diiodo- (8CI)(9CI) EINECS 210-915-9 NSC 80411 (CAS 625-88-7)
- 2,4-Dichloro-5-fluorobenzonitrile (CAS 128593-93-1)
- Methyl 1-(2-fluorophenoxy)cyclobutanecarboxylate (CAS 1993324-17-6)
- 3-(2-Aminophenyl)-5-(trifluoromethyl)-1,3-oxazolidin-2-one (CAS 1376282-88-0)
- 2-(4-Bromophenyl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid (CAS 1282577-02-9)
- 2-(2-Chlorophenyl)-2,3-dihydroquinolin-4(1H)-one (CAS 668998-36-5)
- N-(4-fluorophenyl)-2-(3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazole-4-carboxamide (CAS 956753-84-7)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
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