5-(2-Fluorophenyl)-1,3,4-oxadiazole-2-thiol CAS 108413-51-0
| CAS No. | 108413-51-0 |
| Molecular Formula | C8H5FN2OS |
| Molecular Weight | 196.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2-Fluorophenyl)-1,3,4-oxadiazole-2-thiol (CAS 108413-51-0) is a high-purity analytical reference standard with the molecular formula C8H5FN2OS and a molecular weight of 196.20 g/mol.
The molecular framework of 5-(2-Fluorophenyl)-1,3,4-oxadiazole-2-thiol (C8H5FN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5FN2OS |
| Molecular Weight | 196.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 3-(3-Fluorophenyl)-1,2,4-thiadiazol-5(4H)-one (CAS 1206969-22-3)
- 3-(3-Fluorophenyl)-1,2,4-oxadiazole-5-thiol (CAS 1342386-00-8)
- 1-(3-Fluorophenyl)-1H-tetrazole-5-thiol (CAS 14210-42-5)
- 1-(4-Fluorophenyl)-1H-tetrazole-5-thiol (CAS 1544-79-2)
- N-(4-Fluorophenyl)-1,2,3,4-thiatriazol-5-amine (CAS 1544-80-5)
- 5-(4-Fluorophenyl)-1,3,4-oxadiazole-2(3H)-thione (CAS 41421-13-0)
- Ethyl 2-(3-fluorophenyl)-2-oxoacetate (CAS 110193-59-4)
- Methyl 3-(3-fluorophenyl)oxirane-2-carboxylate (CAS 126119-23-1)
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