Ethyl 2-amino-4-chloro-5-methoxybenzoate CAS 108494-83-3
| CAS No. | 108494-83-3 |
| Molecular Formula | C10H12ClNO3 |
| Molecular Weight | 229.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 229.66 g/mol gives Ethyl 2-amino-4-chloro-5-methoxybenzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2-amino-4-chloro-5-methoxybenzoate (CAS 108494-83-3), molecular formula C10H12ClNO3 and molecular weight 229.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 2-amino-4-chloro-5-methoxybenzoate (C10H12ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-amino-4-chloro-5-methoxybenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO3 |
| Molecular Weight | 229.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
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- Ethyl 2-amino-4-chloro-3-methoxybenzoate (CAS 1247605-97-5)
- 3-Amino-3-(7-chlorobenzo[d][1,3]dioxol-5-yl)propan-1-ol (CAS 1250089-97-4)
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Recommended Standards
- 4-Chloro-2-methyl-5-morpholinopyridazin-3(2h)-one (CAS 1080-85-9)
- 1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene, 97% (CAS 1032903-50-6)
- Methyl 2-{[(5-chloro-2-hydroxyphenyl)methyl]amino}acetate (CAS 1019577-98-0)
- Ethyl 2-chloro-4-(ethylamino)pyrimidine-5-carboxylate (CAS 1138322-14-1)
- Methyl 8-bromo-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate (CAS 823225-66-7)
- 4-((1-(Bromomethyl)cyclohexyl)oxy)tetrahydro-2h-pyran (CAS 1248133-32-5)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-fluoropyridine (CAS 1805314-26-4)
- (3-Allyl-2,4-dioxo-1,3-thiazolidin-5-yl)acetic acid (CAS 868212-21-9)
- 7-Methylbenzo[d][1,2,3]thiadiazole (CAS 78805-01-3)
- Desvenlafaxine Impurity 3 (CAS CATO-C4X-16103)
- 2-Bromo-4-(difluoromethyl)-5-iodopyridine (CAS 1806781-50-9)
- (2,5-Bis(trifluoromethyl)phenyl)methanol (CAS 302911-97-3)
- 5-Methoxy-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one (CAS 180160-90-1)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
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