6-Chloro-N-methylpyrazine-2-carboxamide CAS 1086110-83-9
| CAS No. | 1086110-83-9 |
| Molecular Formula | C6H6ClN3O |
| Molecular Weight | 171.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 171.58 g/mol gives 6-Chloro-N-methylpyrazine-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Chloro-N-methylpyrazine-2-carboxamide (CAS 1086110-83-9) is a high-purity analytical reference standard with the molecular formula C6H6ClN3O and a molecular weight of 171.58 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 6-Chloro-N-methylpyrazine-2-carboxamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 171.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClN3O |
| Molecular Weight | 171.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-chloro-4-hydroxybenzamide (CAS 1007578-86-0)
- 4-Chloro-2-methoxynicotinaldehyde (CAS 1008451-58-8)
- 6-Chloro-N'-hydroxypicolinimidamide (CAS 1042151-12-1)
- 2-Chloro-4-hydroxybenzamide (CAS 1046818-83-0)
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- 4-Chloro-5-methoxypyridine-2-carbaldehyde (CAS 1060801-63-9)
- 2-Chloro-5-methoxyisonicotinaldehyde (CAS 1060801-65-1)
- 6-Chloro-5-methoxynicotinaldehyde (CAS 1060801-67-3)
Recommended Standards
- 2-Cyclopropyl-1,3-oxazole-4-carbonyl chloride (CAS 1072103-26-4)
- 3-Amino-2-chlorobenzoic Acid (CAS 108679-71-6)
- 6-chloro-3-[(hydroxyimino)methyl]pyridin-2-amine (CAS 1062369-45-2)
- 5-Chloro-2-methylnicotinic Acid (CAS 1092286-30-0)
- N-(9,9-dimethyl-9H-fluoren-2-yl)dibenzo[b,d]furan-2-amine (CAS 1359833-89-8)
- Phenacetin (CAS 62-44-2)
- D-Methionine-d3 (S-methyl-d3) (CAS 284665-18-5)
- 2-(6-(Oxiran-2-yl)hexyl)aziridine (CAS 1534354-28-3)
- 3-((1-(Furan-2-yl)ethyl)amino)tetrahydrothiophene 1,1-dioxide (CAS 1019609-85-8)
- (2R)-3-Methoxybutan-2-amine (CAS 1372901-04-6)
- 3-Formylphenyl cyclopropanecarboxylate (CAS 590357-04-3)
- 3-Ethynyl-3-hydroxy-1-methylpiperidin-2-one (CAS 1394119-72-2)
- 7-Hydroxy-3-(4-methoxyphenyl)-8-(morpholinomethyl)-4H-chromen-4-one (CAS 845635-80-5)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
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