5-(4-tert-Butylphenyl)-1,2,4-thiadiazol-3-amine CAS 1086385-86-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-tert-Butylphenyl)-1,2,4-thiadiazol-3-amine.

5-(4-tert-Butylphenyl)-1,2,4-thiadiazol-3-amine (CAS 1086385-86-5) is a high-purity analytical reference standard with the molecular formula C12H15N3S and a molecular weight of 233.33 g/mol.

5-(4-tert-Butylphenyl)-1,2,4-thiadiazol-3-amine (C12H15N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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