2-Cbz-2,6-diazaspiro[4.5]decane CAS 1086394-79-7
| CAS No. | 1086394-79-7 |
| Molecular Formula | C16H22N2O2 |
| Molecular Weight | 274.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Cbz-2,6-diazaspiro[4.5]decane (CAS 1086394-79-7), a certified reference material (molecular formula C16H22N2O2, MW 274.36 g/mol) for analytical method development and quality control.
The molecular framework of 2-Cbz-2,6-diazaspiro[4.5]decane (C16H22N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H22N2O2 |
| Molecular Weight | 274.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Cbz Standards
- Benzyl 2,8-diazaspiro[4.5]decane-8-carboxylate (CAS 1086394-65-1)
- Benzyl 2,8-diazaspiro[4.5]decane-2-carboxylate (CAS 1086394-68-4)
- Benzyl 2,7-diazaspiro[4.5]Decane-7-carboxylate (CAS 1086394-70-8)
- 2-Cbz-2,7-diazaspiro[4.5]decane (CAS 1086394-72-0)
- Benzyl 2,6-diazaspiro[4.5]decane-6-carboxylate (CAS 1086394-76-4)
- Benzyl 1,7-diazaspiro[4.5]decane-7-carboxylate (CAS 1086394-93-5)
- Benzyl 1,7-diazaspiro[4.5]decane-1-carboxylate (CAS 1086394-95-7)
- Benzyl 1,8-diazaspiro[4.5]decane-1-carboxylate (CAS 1158750-29-8)
Recommended Standards
- tert-Butyl 6'-amino-3',4'-dihydro-2'H-spiro[cyclopropane-1,1'-isoquinoline]-2'-carboxylate (CAS 1092794-29-0)
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- tert-Butyl 2-(2-methyl-1h-indol-1-yl)ethylcarbamate (CAS 1105192-83-3)
- N-(benzo[d]thiazol-2-ylmethyl)thiophene-2-carboxamide (CAS 1060984-43-1)
- Hypaconine (CAS 63238-68-6)
- L-tyrosyl-L-phenylalanyl-L-phenylalanine compound with acetic acid (1:1) (CAS 108322-09-4)
- Ethyl N-[(2E)-2-[2-(3-methoxyphenyl)hydrazin-1-ylidene]-3-oxobutanoyl]carbamate (CAS 338400-93-4)
- 2-(5-chloro-2-ethoxyphenyl)ethan-1-amine (CAS 910380-95-9)
- (3R,5S)-3-Amino-5-ethylpyrrolidine-3-carboxylic acid (CAS 754951-06-9)
- 4-Chloro-3-methyl-2,3-dihydro-1H-inden-1-one (CAS 54795-06-1)
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