2-Bromo-5-chloro-4-methyl-3-nitropyridine CAS 1086838-26-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1086838-26-7
Molecular FormulaC6H4BrClN2O2
Molecular Weight251.47 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-5-chloro-4-methyl-3-nitropyridine CAS 1086838-26-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-chloro-4-methyl-3-nitropyridine.

2-Bromo-5-chloro-4-methyl-3-nitropyridine (CAS 1086838-26-7) is a high-purity analytical reference standard with the molecular formula C6H4BrClN2O2 and a molecular weight of 251.47 g/mol.

The molecular framework of 2-Bromo-5-chloro-4-methyl-3-nitropyridine (C6H4BrClN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 2-Bromo-5-chloro-4-methyl-3-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4BrClN2O2
Molecular Weight251.47 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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