Amiodarone EP Impurity G CAS 1087223-70-8
| CAS No. | 1087223-70-8 |
| Molecular Formula | C26H31I2NO4 |
| Molecular Weight | 675.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Amiodarone EP Impurity G (CAS 1087223-70-8, C26H31I2NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Amiodarone EP Impurity G (C26H31I2NO4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 675.34 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Amiodarone EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H31I2NO4 |
| Molecular Weight | 675.34 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Amiodarone Standards
- Amiodarone Didesethyl Impurity (CAS 94317-95-0)
- Amiodarone Impurity 16 (CAS 318267-30-0)
- Amiodarone Impurity 21 (CAS CATO-C4X-142521)
- Amiodarone Impurity 30 (CAS CATO-C4X-142530)
- Amiodarone Impurity 20 (CAS CATO-C4X-142520)
- Amiodarone (CAS 1951-25-3)
- Amiodarone EP Impurity B (CAS 83409-32-9)
- Amiodarone Impurity 33 (CAS CATO-C4X-142533)
Recommended Standards
- n-Octatetracontane (CAS 7098-26-2)
- Nickel, [5,10,15,20-tetra-4-pyridinyl-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]-, (SP-4-1)- (CAS 14514-68-2)
- (Z)-2,2,4-Trimethylpentane-1,3-diyl dioleate (CAS 68201-79-6)
- 2,4,6-Tris((perfluorophenyl)thio)-1,3,5-triazine (CAS 922517-12-2)
- Roxatidine Impurity 11 (CAS CATO-C4X-121311)
- Molnupiravir Impurity 4 (CAS 2346620-55-9)
- Apixaban Impurity 153 (CAS CATO-C4X-1088153)
- Methyl Trans-10-Pentadecenoate(C15:1T) (CAS 90176-51-5)
- Lactulose (CAS 4618-18-2)
- Mifepristone Impurity 14 (CAS 84371-69-7)
- Teprenone Impurity 24 (CAS CATO-C4X-208124)
- Mitiglinide Impurity 5 (CAS CATO-C4X-11615)
- 4-(4-(2-Methoxyethyl)phenyl)thiazol-2-amine (CAS 847781-97-9)
- Neuropeptide K, porcine (CAS 106441-70-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com