5-(3-(2-Chloropyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-methoxybenzamide CAS 1089278-50-1
| CAS No. | 1089278-50-1 |
| Molecular Formula | C25H16ClF2N5O2 |
| Molecular Weight | 491.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(3-(2-Chloropyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-methoxybenzamide (C25H16ClF2N5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-(3-(2-Chloropyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-methoxybenzamide (CAS 1089278-50-1) is a high-purity analytical reference standard with the molecular formula C25H16ClF2N5O2 and a molecular weight of 491.88 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(3-(2-Chloropyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-methoxybenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H16ClF2N5O2 |
| Molecular Weight | 491.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloropyrimidin Standards
- (R)-2-(4-(5-chloropyrimidin-2-yl)piperidin-1-yl)-4-((1-(hydroxymethyl)cyclobutyl)amino)-6,7-dihydrothieno[3,2-d]pyrimidine 5-oxide (CAS 1423719-30-5)
- 5-(2-(2-Chloropyrimidin-4-yl)acetyl)-N-(2,6-difluorophenyl)-2-methoxybenzamide (CAS 1089278-52-3)
- (S)-1-(5-Chloropyrimidin-2-yl)-N-(2,4-dichlorobenzyl)pyrrolidin-3-amine (CAS 885103-97-9)
- (S)-8-(1-((6-Chloropyrimidin-4-yl)amino)propan-2-yl)-N-methylquinoline-4-carboxamide (CAS 1476076-42-2)
- 2-((4-Chloropyrimidin-5-yl)oxy)-5-fluoro-N,N-diisopropylbenzamide (CAS 2169919-97-3)
- 2-((4-Chloropyrimidin-5-yl)oxy)-N-ethyl-5-fluoro-N-isopropylbenzamide (CAS 2169923-04-8)
- 3-(2-Chloropyrimidin-4-yl)-1-(cyclopropylsulfonyl)-1h-indole (CAS 1835670-20-6)
- (6-Chloropyrimidin-4-yl)-N-(tert-butoxycarbonyl)carbamic acid tert-butyl ester (CAS 354112-08-6)
Recommended Standards
- (2S,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6S)-6-((6-chloro-1H-indol-3-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 425427-87-8)
- N-Desmethyl Asenapine N-Carbamoyl Glucuronide (CAS 128923-28-4)
- 5,5'-Bis(trimethylstannyl)-2,2'-bithiophene, 99% (CAS 143367-56-0)
- 5-((4-Chlorophenyl)thio)-4-(((2,6-dichlorophenyl)thio)methyl)-1-methyl-3-phenyl-1H-pyrazole (CAS 318951-85-8)
- Exo-8-(tert-Butoxycarbonyl)-8-azabicyclo[3.2.1]octane-3-carboxylic acid (CAS 280762-00-7)
- Piperidine D10 Hydrochloride (CAS 339080-76-1)
- 2-(pyridin-2-ylsulfanyl)acetic acid (CAS 10002-29-6)
- Benzyl ((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-3-yl)(cyclopropyl)carbamate (CAS 1401666-66-7)
- 7-tert-butylazepan-2-one (CAS 155204-32-3)
- Methyl 2-hydroxy-3-(methylthio)propanoate (CAS 54864-75-4)
- 1-(2,3-Dihydro-1h-inden-5-yl)-2-(methylthio)ethan-1-one (CAS 1178464-41-9)
- 6-(Difluoromethyl)-2,3-difluoroisonicotinic acid (CAS 1806016-49-8)
- 2-Allylazetidine hydrochloride (CAS 2137887-18-2)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com