Indocyanine Green Impurity 10 CAS 109-70-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.109-70-6
Molecular FormulaC3H6BrCl
Molecular Weight157.44 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Indocyanine Green Impurity 10 CAS 109-70-6 chemical structure

Description

Owing to chlorine/bromine substitution, Indocyanine Green Impurity 10 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 157.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a process- or degradation-related impurity, Indocyanine Green Impurity 10 (CAS 109-70-6, C3H6BrCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC3H6BrCl
Molecular Weight157.44 g/mol
Purity>95%
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1957
Halogen ContentCl/Br-containing

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