4-(4-CHloro-2-fluorobenzoyl)morpholine CAS 1090530-77-0
| CAS No. | 1090530-77-0 |
| Molecular Formula | C11H11ClFNO2 |
| Molecular Weight | 243.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(4-CHloro-2-fluorobenzoyl)morpholine (CAS 1090530-77-0), molecular formula C11H11ClFNO2 and molecular weight 243.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-CHloro-2-fluorobenzoyl)morpholine (C11H11ClFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11ClFNO2 |
| Molecular Weight | 243.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- Tert-butyl (2R,4S)-4-amino-2-(methoxymethyl)pyrrolidine-1-carboxylate (CAS 1932561-50-6)
- Oxazol-2-ylmethanamine hydrochloride (CAS 1041053-44-4)
- Cyclopropyl(2,6-difluorophenyl)methanone (CAS 1343158-95-1)
- 2-(2-(Benzyloxy)-3-chloro-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121512-22-7)
- 6-Ethoxypyridine-3-boronic Acid (CAS 612845-44-0)
- Arbidol Impurity 52 (CAS CATO-C4X-112952)
- 3-(4-Piperidinyl)-1,2-benzisoxazole N-Carbamic Acid Phenyl Ester (CAS 84163-21-3)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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