(3-Fluoro-4-methylphenyl)(4-hydroxypiperidin-1-yl)methanone CAS 1090595-85-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1090595-85-9
Molecular FormulaC13H16FNO2
Molecular Weight237.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3-Fluoro-4-methylphenyl)(4-hydroxypiperidin-1-yl)methanone CAS 1090595-85-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3-Fluoro-4-methylphenyl)(4-hydroxypiperidin-1-yl)methanone.

CATO supplies (3-Fluoro-4-methylphenyl)(4-hydroxypiperidin-1-yl)methanone (CAS 1090595-85-9), a certified reference material (molecular formula C13H16FNO2, MW 237.27 g/mol) for analytical method development and quality control.

(3-Fluoro-4-methylphenyl)(4-hydroxypiperidin-1-yl)methanone (C13H16FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H16FNO2
Molecular Weight237.27 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms1

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