3-Fluoro-N-((4-(2-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)benzamide CAS 1091128-65-2
| CAS No. | 1091128-65-2 |
| Molecular Formula | C20H22FNO3 |
| Molecular Weight | 343.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Fluoro-N-((4-(2-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)benzamide.
3-Fluoro-N-((4-(2-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)benzamide (CAS 1091128-65-2) is a high-purity analytical reference standard with the molecular formula C20H22FNO3 and a molecular weight of 343.39 g/mol.
The molecular framework of 3-Fluoro-N-((4-(2-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)benzamide (C20H22FNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H22FNO3 |
| Molecular Weight | 343.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- Benzyl 2-(4-fluoro-2-methylphenyl)-4-hydroxypiperidine-1-carboxylate (CAS 2306274-95-1)
- N-[3-Fluoro-4-(4-phenylpiperazin-1-yl)phenyl]-2-methoxyacetamide (CAS 866136-83-6)
- 5-Fluoro-N-(furan-3-ylmethyl)-2-methoxy-N-(2-methoxyethyl)benzenesulfonamide (CAS 1421512-45-9)
- (S)-5-Fluoro-1-(2-fluorophenyl)-3-(piperidin-3-ylmethoxy)-1H-indazole (CAS 888951-64-2)
- {5-fluoro-1-[tris(propan-2-yl)silyl]-1H-indol-4-yl}boronic acid (CAS 2304635-01-4)
- 6-Fluoro-7-(piperazin-1-yl)-N-(thiophen-3-ylmethyl)quinazolin-4-amine (CAS 625080-70-8)
- 5-Fluoro-N-(2-(4-fluorophenoxy)ethyl)-2-methoxybenzenesulfonamide (CAS 1105220-78-7)
- 4-Fluoro-N-(2-phenylquinazolin-4-yl)benzamide (CAS 866155-25-1)
Recommended Standards
- 2-((4-Fluorobenzyl)amino)-4-(4-isopropylphenyl)-4-oxobutanoic acid (CAS 1024697-65-1)
- N-(4-Fluorobenzyl)-4-(2-methoxyphenyl)tetrahydro-2H-pyran-4-carboxamide (CAS 1091138-65-6)
- N-(2,4-Difluorophenyl)(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonamide (CAS 1022105-84-5)
- (E)-3-[4-(3-Fluoropropoxy)phenyl]-N-(4-methoxybenzyl)-2-propenamide (CAS 1164562-17-7)
- 3-Sulfated Lewis A (CAS 153088-71-2)
- Cyclovirobuxine C (CAS 30276-35-8)
- 2-(4-methanesulfonylphenyl)morpholine hydrochloride (CAS 2031269-26-6)
- Methyl 3-(2,6-dichlorophenyl)-5-(1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole-4-carboxylate (CAS 321571-24-8)
- 4-Formylphenyl 1-naphthoate (CAS 331253-68-0)
- Methyl (Z)-2-cyano-2-(6-oxaspiro[4.5]decan-9-ylidene)acetate (CAS 1467617-14-6)
- (2E)-3-(4-Aminophenyl)-1-(4-fluorophenyl)prop-2-en-1-one (CAS 958456-78-5)
- 8-CHLORO-1H-PYRIDO[2,3-B][1,4]OXAZIN-2(3H)-ONE (CAS 1198154-62-9)
- Ketoprofen Impurity 85 (CAS CATO-C4X-147185)
- Neuropeptide FF (CAS 99566-27-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com